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About me

I work in the Uhlén group at Molecular Neurobiology (MBB).


MD-PhD student at Karolinska Institutet

MSc in engineering physics at KTH

Research description

Development of neural networks, both in vitro and in silico. Foundations of calcium signaling/oscillations (frequency decoding).

CO2-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture.
Forsberg D, Horn Z, Tserga E, Smedler E, Silberberg G, Shvarev Y, et al
Elife 2016 Jul;5():

The 1p36 Tumor Suppressor KIF 1Bβ Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and Apoptosis.
Li S, Fell S, Surova O, Smedler E, Wallis K, Chen Z, et al
Dev. Cell 2016 Jan;36(2):164-78

Calcium signaling in neocortical development.
Uhlén P, Fritz N, Smedler E, Malmersjö S, Kanatani S
Dev Neurobiol 2015 Apr;75(4):360-8

Network analysis of time-lapse microscopy recordings.
Smedler E, Malmersjö S, Uhlén P
Front Neural Circuits 2014 ;8():111

Cathelicidin LL-37 induces time-resolved release of LTB4 and TXA2 by human macrophages and triggers eicosanoid generation in vivo.
Wan M, Soehnlein O, Tang X, van der Does A, Smedler E, Uhlén P, et al
FASEB J. 2014 Aug;28(8):3456-67

Frequency decoding of calcium oscillations.
Smedler E, Uhlén P
Biochim. Biophys. Acta 2014 Mar;1840(3):964-9

Small-world networks of spontaneous Ca(2+) activity.
Malmersjö S, Rebellato P, Smedler E, Uhlén P
Commun Integr Biol 2013 Jul;6(4):e24788

Co-first author

Neural progenitors organize in small-world networks to promote cell proliferation.
Malmersjö S, Rebellato P, Smedler E, Planert H, Kanatani S, Liste I, et al
Proc. Natl. Acad. Sci. U.S.A. 2013 Apr;110(16):E1524-32

Co-first author

Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish heart.
Kitambi S, Nilsson E, Sekyrova P, Ibarra C, Tekeoh G, Andäng M, et al
BMC Physiol. 2012 Mar;12():3

Co-first author

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