Erika Bereczki

About me
Publications
CV
Public outreach and news

About me

I have PhD in theoretical medical sciences from the University of Szeged
where I graduated in 2007.

Research

My research interest can be broadly described as dementia research focusing
on understanding the mechanism and consequences of dementia, improving
differential diagnosis and predicting cognitive decline in Alzheimer's
disease and Lewy body dementias with particular interest in synaptic proteins
and their role in dementia progression. Lately, humbled by the impact of
SARS-Cov-2 I have joined the National Pandemic center of KI as a research
specialist contributing to the increased diagnostic and sequencing capacity
of Covid-19 in Sweden, aiming to understand the needs and means of responding
to future pandemics.

Articles

Article: MOLECULAR PSYCHIATRY. 2023;28(9):3966-3981

Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models.

Naia L; Shimozawa M; Bereczki E; Li X; Liu J; Jiang R; Giraud R; Leal NS; Pinho CM; Berger E; Falk VL; Dentoni G; Ankarcrona M; Nilsson P
Article: BIOLOGY-BASEL. 2023;12(6):805

The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer's Disease in AppNL-G-F Knock-In Mice.

Medina-Vera D; Zhao H; Bereczki E; Rosell-Valle C; Shimozawa M; Chen G; de Fonseca FR; Nilsson P; Tambaro S
Article: BRAIN COMMUNICATIONS. 2022;5(1):fcad001

Translational potential of synaptic alterations in Alzheimer's disease patients and amyloid precursor protein knock-in mice.

Medina-Vera D; Enache D; Tambaro S; Abuhashish E; Rosell-Valle C; Winblad B; Rodríguez de Fonseca F; Bereczki E; Nilsson P
Article: MOLECULAR PSYCHIATRY. 2022;27(8):3247-3261

Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia.

Mätlik K; Garton DR; Montaño-Rodríguez AR; Olfat S; Eren F; Casserly L; Damdimopoulos A; Panhelainen A; Porokuokka LL; Kopra JJ; Turconi G; Schweizer N; Bereczki E; Piehl F; Engberg G; Cervenka S; Piepponen TP; Zhang F-P; Sipilä P; Jakobsson J; Sellgren CM; Erhardt S; Andressoo J-O
Article: SCIENTIFIC DATA. 2021;8(1):312

Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis.

Haytural H; Benfeitas R; Schedin-Weiss S; Bereczki E; Rezeli M; Unwin RD; Wang X; Dammer EB; Johnson ECB; Seyfried NT; Winblad B; Tijms BM; Visser PJ; Frykman S; Tjernberg LO
Article: BRAIN COMMUNICATIONS. 2021;3(2):fcab049

Presynaptic accumulation of α-synuclein causes synaptopathy and progressive neurodegeneration in Drosophila.

Bridi JC; Bereczki E; Smith SK; Poças GM; Kottler B; Domingos PM; Elliott CJ; Aarsland D; Hirth F
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;77(3):1143-1155

Increased Cerebrospinal Fluid Concentration of ZnT3 Is Associated with Cognitive Impairment in Alzheimer's Disease.

Enache D; Pereira JB; Jelic V; Winblad B; Nilsson P; Aarsland D; Bereczki E
Article: BRAIN. 2018;141(2):582-595

Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach.

Bereczki E; Branca RM; Francis PT; Pereira JB; Baek J-H; Hortobágyi T; Winblad B; Ballard C; Lehtiö J; Aarsland D
Article: ORVOSI HETILAP. 2017;158(17):643-652

[Clinical and neuropathological characteristics of dementia with Lewy bodies].

Bencze J; Simon V; Bereczki E; Majer R; Varkoly G; Murnyák B; Kálmán J; Hortobágyi T
Article: NPJ PARKINSONS DISEASE. 2017;3:7

Synaptic proteins in CSF relate to Parkinson's disease stage markers.

Bereczki E; Bogstedt A; Höglund K; Tsitsi P; Brodin L; Ballard C; Svenningsson P; Aarsland D
Article: ALZHEIMERS & DEMENTIA. 2016;12(11):1149-1158

Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.

Bereczki E; Francis PT; Howlett D; Pereira JB; Höglund K; Bogstedt A; Cedazo-Minguez A; Baek J-H; Hortobágyi T; Attems J; Ballard C; Aarsland D
Article: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 2016;42(4):352-365

Unfolded protein response is activated in Lewy body dementias.

Baek J-H; Whitfield D; Howlett D; Francis P; Bereczki E; Ballard C; Hortobágyi T; Attems J; Aarsland D
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1853(7):1646-1657

mTor mediates tau localization and secretion: Implication for Alzheimer's disease.

Tang Z; Ioja E; Bereczki E; Hultenby K; Li C; Guan Z; Winblad B; Pei J-J
Article: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2015;11(2):421-430

Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice.

Ordóñez-Gutiérrez L; Re F; Bereczki E; Ioja E; Gregori M; Andersen AJ; Antón M; Moghimi SM; Pei J-J; Masserini M; Wandosell F
Article: METABOLIC BRAIN DISEASE. 2014;29(3):729-736

mTOR-mediated hyperphosphorylation of tau in the hippocampus is involved in cognitive deficits in streptozotocin-induced diabetic mice.

Wang S; Zhou S-L; Min F-Y; Ma J-J; Shi X-J; Bereczki E; Wu J
Article: JOURNAL OF PROTEOME RESEARCH. 2014;13(5):2433-2444

mTor is a signaling hub in cell survival: a mass-spectrometry-based proteomics investigation.

Tang Z; Baykal AT; Gao H; Quezada HC; Zhang H; Bereczki E; Serhatli M; Baykal B; Acioglu C; Wang S; Ioja E; Ji X; Zhang Y; Guan Z; Winblad B; Pei J-J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(22):15556-15570

Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer disease.

Tang Z; Bereczki E; Zhang H; Wang S; Li C; Ji X; Branca RM; Lehtiö J; Guan Z; Filipcik P; Xu S; Winblad B; Pei J-J
Article: PLOS ONE. 2012;7(9):e46007

Increased tau phosphorylation and impaired presynaptic function in hypertriglyceridemic ApoB-100 transgenic mice.

Lénárt N; Szegedi V; Juhász G; Kasztner A; Horváth J; Bereczki E; Tóth ME; Penke B; Sántha M
Article: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2011;7(5):560-571

Liposomes functionalized with acidic lipids rescue Aβ-induced toxicity in murine neuroblastoma cells.

Bereczki E; Re F; Masserini ME; Winblad B; Pei JJ
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2011;89(8):1267-1275

Interplay between glycogen synthase kinase-3β and tau in the cerebellum of Hsp27 transgenic mouse.

Wang S; Toth ME; Bereczki E; Santha M; Guan Z-Z; Winblad B; Pei J-J
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2010;48(4):649-652

Biglycan protects cardiomyocytes against hypoxia/reoxygenation injury: role of nitric oxide.

Csont T; Görbe A; Bereczki E; Szunyog A; Aypar E; Tóth ME; Varga ZV; Csonka C; Fülöp F; Sántha M; Ferdinandy P
Article: EXPERIMENTAL EYE RESEARCH. 2009;89(2):178-186

Bruch's membrane changes in transgenic mice overexpressing the human biglycan and apolipoprotein b-100 genes.

Sallo FB; Bereczki E; Csont T; Luthert PJ; Munro P; Ferdinandy P; Sántha M; Lengyel I
Article: HEPATOLOGY. 2009;50(1):77-84

Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance.

Su Q; Tsai J; Xu E; Qiu W; Bereczki E; Santha M; Adeli K
Article: LIFE SCIENCES. 2009;84(25-26):935-939

Capillary injury in the ischemic brain of hyperlipidemic, apolipoprotein B-100 transgenic mice.

Süle Z; Mracskó E; Bereczki E; Sántha M; Csont T; Ferdinandy P; Bari F; Farkas E
Article: NEUROCHEMISTRY INTERNATIONAL. 2008;53(6-8):309-316

CB(2) cannabinoid receptor antagonist SR144528 decreases mu-opioid receptor expression and activation in mouse brainstem: role of CB(2) receptor in pain.

Páldy E; Bereczki E; Sántha M; Wenger T; Borsodi A; Zimmer A; Benyhe S
Article: JOURNAL OF PROTEOME RESEARCH. 2008;7(6):2246-2252

Overexpression of human apolipoprotein B-100 induces severe neurodegeneration in transgenic mice.

Bereczki E; Bernát G; Csont T; Ferdinandy P; Scheich H; Sántha M
Article: NEUROCHEMISTRY INTERNATIONAL. 2008;52(1-2):321-328

Noladin ether, a putative endocannabinoid, inhibits mu-opioid receptor activation via CB2 cannabinoid receptors.

Páldyová E; Bereczki E; Sántha M; Wenger T; Borsodi A; Benyhe S
Article: CONNECTIVE TISSUE RESEARCH. 2008;49(3):129-132

The role of biglycan in the heart.

Bereczki E; Sántha M
Article: CARDIOVASCULAR RESEARCH. 2007;76(1):100-109

Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice.

Csont T; Bereczki E; Bencsik P; Fodor G; Görbe A; Zvara A; Csonka C; Puskás LG; Sántha M; Ferdinandy P
Article: JOURNAL OF PROTEOME RESEARCH. 2007;6(2):854-861

Overexpression of biglycan in the heart of transgenic mice: an antibody microarray study.

Bereczki E; Gonda S; Csont T; Korpos E; Zvara A; Ferdinandy P; Santha M
Article: BIOLOGIA FUTURA. 2007;58 Suppl:113-129

Altered gene expression and functional activity of opioid receptors in the cerebellum of CB1 cannabinoid receptor knockout mice after acute treatments with cannabinoids.

Páldyová E; Bereczki E; Sántha M; Wenger T; Borsodi A; Benyhe S
Article: NEUROCHEMISTRY INTERNATIONAL. 2007;50(1):1-4

APP mRNA splicing is upregulated in the brain of biglycan transgenic mice.

Bjelik A; Pákáski M; Bereczki E; Gonda S; Juhász A; Rimanóczy A; Zana M; Janka Z; Sántha M; Kálmán J
Article: NEUROCHEMISTRY INTERNATIONAL. 2006;49(4):393-400

Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis.

Bjelik A; Bereczki E; Gonda S; Juhász A; Rimanóczy A; Zana M; Csont T; Pákáski M; Boda K; Ferdinandy P; Dux L; Janka Z; Sántha M; Kálmán J
Article: BIOCHIMIE. 2004;86(11):817-824

Cholesterol and cholesterol plus DHA diet-induced gene expression and fatty acid changes in mouse eye and brain.

Puskás LG; Bereczki E; Sántha M; Vigh L; Csanádi G; Spener F; Ferdinandy P; Onochy A; Kitajka K
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All other publications

Corrigendum: BRAIN. 2019;142(6):e24

Corrigendum.
Review: CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2015;15(22):2267-2276

Comparison of Various Types of Ligand Decorated Nanoliposomes for their Ability to Inhibit Amyloid Aggregation and to Reverse Amyloid Cytotoxicity.

Markoutsa E; Mourtas S; Bereczki E; Zona C; La Ferla B; Nicotra F; Flores O; Pei J-J; Antimisiaris SG
Review: JOURNAL OF ALZHEIMERS DISEASE. 2013;37(3):495-505

Dysregulated mTOR-dependent signaling in neurodegeneration or carcinogenesis: implication for Alzheimer's disease and brain tumors.

Wang S; Wu J; Nie S-D; Bereczki E; Pei J-J

Employments

Affiliated to Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2024-2024
Research Specialist, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2022-2024

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