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Elizabeth Arkema

Assistant professor

Visiting address : Eugeniahemmet, T2, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm, Sweden
Postal address : Department of Medicine, Solna (MedS), K2, Group J Askling, Eugeniahemmet, T2, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm, Sweden
Delivery address : Eugeniahemmet, T2, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm, Sweden


ScD Harvard School of Public Health

ScM Harvard School of Public Health

AB Princeton University

Research description

My research is focused on the epidemiology of rheumatic diseases. My work includes studying the occurrence of comorbidity after rheumatoid arthritis onset and in relation to treatment as well as risk factors for and outcomes related to systemic lupus erythematosus. I am currently building a national research program to understand the epidemiology of sarcoidosis in Sweden while continuing to investigate outcomes in patients with systemic lupus such as stroke and infection. 

Teaching portfolio

Co-organizer of Systematic Reviews and Meta-analyses (nr. 2790)



Case definitions in Swedish register data to identify systemic lupus erythematosus
Arkema Ev, Jönsen A, Rönnblom L, Svenungsson E, Sjöwall C, Simard Jf
BMJ open 2016;6(1):e007769-

Endometriosis and systemic lupus erythematosus: a population-based case-control study
Harris Hr, Simard Jf, Arkema Ev
Lupus 2016;25(9):1045-9

Induction maintenance with tumour necrosis factor-inhibitor combination therapy with discontinuation versus methotrexate monotherapy in early rheumatoid arthritis: a systematic review and meta-analysis of efficacy in randomised controlled trials
Emamikia S, Arkema Ev, Györi N, Detert J, Chatzidionysiou K, Dougados M, et al
RMD open 2016;2(2):e000323-

Sarcoidosis incidence and prevalence: a nationwide register-based assessment in Sweden
Arkema Ev, Grunewald J, Kullberg S, Eklund A, Askling J
The European respiratory journal 2016;48(6):1690-1699

Sex Ratio of Offspring Born to Women With Systemic Lupus Erythematosus or Rheumatoid Arthritis
Arkema Ev, Askling J, Salmon Je, Simard Jf
Arthritis & rheumatology (Hoboken, N.J.) 2016;():-

What to Expect When Expecting With Systemic Lupus Erythematosus (SLE): A Population-Based Study of Maternal and Fetal Outcomes in SLE and Pre-SLE
Arkema Ev, Palmsten K, Sjöwall C, Svenungsson E, Salmon Je, Simard Jf
Arthritis care & research 2016;68(7):988-94

Are patients with rheumatoid arthritis still at an increased risk of tuberculosis and what is the role of biological treatments?
Arkema Ev, Jonsson J, Baecklund E, Bruchfeld J, Feltelius N, Askling J, et al
Annals of the rheumatic diseases 2015;74(6):1212-7

Cohort profile: systemic lupus erythematosus in Sweden: the Swedish Lupus Linkage (SLINK) cohort
Arkema Ev, Simard Jf
BMJ open 2015;5(8):e008259-

Drug survival on TNF inhibitors in patients with rheumatoid arthritis comparison of adalimumab, etanercept and infliximab
Neovius M, Arkema Ev, Olsson H, Eriksson Jk, Kristensen Le, Simard Jf, et al
Annals of the rheumatic diseases 2015;74(2):354-60

Monocyte chemotactic protein-1 elevation prior to the onset of rheumatoid arthritis among women
Arkema Ev, Lu B, Malspeis S, Karlson Ew, Costenbader Kh
Biomarkers in medicine 2015;9(8):723-9

Perinatal risk factors for future SLE: a population-based nested case-control study
Arkema Ev, Simard Jf
Lupus 2015;24(8):869-74

Stroke in systemic lupus erythematosus: a meta-analysis of population-based cohort studies
Holmqvist M, Simard Jf, Asplund K, Arkema Ev
RMD open 2015;1(1):e000168-

Being overweight or obese and risk of developing rheumatoid arthritis among women: a prospective cohort study
Lu B, Hiraki Lt, Sparks Ja, Malspeis S, Chen Cy, Awosogba Ja, et al

Circulating 25-hydroxyvitamin D level and risk of developing rheumatoid arthritis
Hiraki Lt, Arkema Ev, Cui J, Malspeis S, Costenbader Kh, Karlson Ew
Rheumatology (Oxford, England) 2014;53(12):2243-8

No association between rheumatoid arthritis, amyotrophic lateral sclerosis, and tumour necrosis factor inhibitor treatment
Arkema Ev, Feltelius N, Olsson T, Askling J, Artis Study Group
Annals of the rheumatic diseases 2014;73(11):2061-2

The Swedish Rheumatology Quality Register: optimisation of rheumatic disease assessments using register-enriched data
Eriksson Jk, Askling J, Arkema Ev

Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case-control study
Arkema Ev, Goldstein Bl, Robinson W, Sokolove J, Wagner Ca, Malspeis S, et al
Arthritis research & therapy 2013;15(5):R159-

Exposure to ultraviolet-B and risk of developing rheumatoid arthritis among women in the Nurses' Health Study
Arkema Ev, Hart Je, Bertrand Ka, Laden F, Grodstein F, Rosner Ba, et al

Patients with ulcerative colitis miss more days of work than the general population, even following colectomy
Neovius M, Arkema Ev, Blomqvist P, Ekbom A, Smedby Ke
Gastroenterology 2013;144(3):536-43

Incidence of progressive multifocal leukoencephalopathy in patients with rheumatoid arthritis: a national population-based study
Arkema Ev, Van Vollenhoven Rf, Askling J, Artis Study Group
Annals of the rheumatic diseases 2012;71(11):1865-7

Is there a sex bias in prescribing anti-tumour necrosis factor medications to patients with rheumatoid arthritis? A nation-wide cross-sectional study
Arkema Ev, Neovius M, Joelsson Jk, Simard Jf, Van Vollenhoven Rf
Annals of the rheumatic diseases 2012;71(7):1203-6

Detection and evaluation of a drug safety signal concerning pancreatic cancer: lessons from a joint approach of three European biologics registers
Strangfeld A, Hyrich K, Askling J, Arkema E, Davies R, Listing J, et al
RHEUMATOLOGY 2011;50(1):146-51

Ten years with biologics: to whom do data on effectiveness and safety apply?
Simard Jf, Arkema Ev, Sundström A, Geborek P, Saxne T, Baecklund E, et al
Rheumatology (Oxford, England) 2011;50(1):204-13

A Prospective Study of Periodontal Disease and Risk of Rheumatoid Arthritis
Arkema Ev, Karlson Ew, Costenbader Kh

Efficacy of initial methotrexate monotherapy versus combination therapy with a biological agent in early rheumatoid arthritis: a meta-analysis of clinical and radiographic remission
Kuriya B, Arkema Ev, Bykerk Vp, Keystone Ec

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