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Research description

Christer Svensén studies the effects of cardiovascular monitoring and fluid treatment for patients prior to, during and after surgery. Hydration based on blood pressure and urine production has often led to the patient storing unnecessary fluids, which affects both morbidity and mortality.

Studies are conducted of infusion solutions' distribution in the body during different pathological conditions, and of non-invasive methods to assess a patient's fluid status and hydration in connection with sepsis and septic shock.

Publications

A mini volume loading test (mVLT) using 2.5-mLkg boluses of crystalloid for indication of perioperative changes in hydration status
Andrijauskas A, Svensen Ch, Porvaneckas N, Šipylaitė J, Stankevičius E, Činčikas D, et al
Medicina (Kaunas, Lithuania) 2016;52(6):354-365

Analgesic effect of a single dose of betamethasone after ambulatory knee arthroscopy: a randomized controlled trial
Segelman J, Pettersson Hj, Svensén C, Divander Mb, Barenius B, Segelman J
Journal of anesthesia 2016;30(5):803-10

Association between fluid balance and mortality in patients with septic shock: a post hoc analysis of the TRISS trial
Cronhjort M, Hjortrup Pb, Holst Lb, Joelsson-alm E, Mårtensson J, Svensen C, et al
Acta anaesthesiologica Scandinavica 2016;60(7):925-33

Monitoring micro-vascular reactivity: a tool for guiding fluid therapy?
Svensen C
Anaesthesia 2016;71(7):747-50

Patients with chronic pain: One-year follow-up of a multimodal rehabilitation programme at a pain clinic
Hållstam A, Löfgren M, Svensén C, Stålnacke Bm
Scandinavian journal of pain 2016;10():36-42

A mini volume loading test for indication of preoperative dehydration in surgical patients
Andrijauskas A, Ivaškevičius J, Porvaneckas N, Stankevičius E, Svensen Ch, Uvarovas V, et al
Medicina (Kaunas, Lithuania) 2015;51(2):81-91

"Change is possible": Patients' experience of a multimodal chronic pain rehabilitation programme
Hållstam A, Stålnacke Bm, Svensen C, Löfgren M
Journal of rehabilitation medicine 2015;47(3):242-8

Endotracheal Intubation With and Without Night Vision Goggles in a Helicopter and Emergency Room Setting: A Manikin Study
Gellerfors M, Svensén C, Linde J, Lossius Hm, Gryth D
Military medicine 2015;180(9):1006-10

The effect of hemodynamic monitoring depends entirely on the action to which it leads
Cronhjort M, Mårtensson J, Joelsson-alm E, Svensen C
Intensive care medicine 2015;41(6):1171-2

The use of a noninvasive hemoglobin monitor for determining fluid distribution and elimination in pediatric patients undergoing minor surgery
Lian Qq, Li Hs, Zeng Rf, Lang Jh, Shangguan Wn, Liu Hc, et al
JOURNAL OF CLINICAL MONITORING AND COMPUTING 2015;29(1):41-6

[EMA-decision on HES-restrictions]
Svensén C, Hjelmqvist H
Lakartidningen 2014;111(1-2):20-

Evaluation of hydration status calculated from differences in venous and capillary plasma dilution during stepwise crystalloid infusions: A randomized crossover study in healthy volunteers
Svensen Ch, Stankevičius E, Broms J, Markevičius V, Andrijauskas A
Medicina (Kaunas, Lithuania) 2014;50(5):255-62

In response
Sjöstrand F, Svensen C
Anesthesia and analgesia 2014;118(2):482-

Isoproternenol increases vascular volume expansion and urinary output after a large crystalloid bolus in healthy volunteers
Asmussen S, Salter M, Prough Ds, Kramer Gc, Svensen C, Sheffield-moore M, et al
Shock (Augusta, Ga.) 2014;42(5):407-14

Micturition problems after bladder distension during hospitalization in Sweden: "I'm not ill, just damaged for the rest of my life"
Joelsson-alm E, Nyman Cr, Svensén C, Ulfvarson J
Nursing research 2014;63(6):418-25

Use of the Airtraq® device for airway management in the prehospital setting--a retrospective study
Gellerfors M, Larsson A, Svensén Ch, Gryth D
Scandinavian journal of trauma, resuscitation and emergency medicine 2014;22():10-

A randomized double-blind clinical trial of tourniquet application strategies for total knee arthroplasty
Kvederas G, Porvaneckas N, Andrijauskas A, Svensen Ch, Ivaskevicius J, Mazunaitis J, et al
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY 2013;21(12):2790-9

[Doubts about HES. The European Medicines Agency withdraws the marketing permit until further notice]
Svensén C
Lakartidningen 2013;110(32-33):1399-

[Prehospital fluid therapy and stabilization in hemorrhagic shock]
Svensén C
Lakartidningen 2013;110(7):340-1

Statistically Biased Calibration Method for the Real-time Adjustment of Noninvasive Haemoglobin Measurements in a Semi-automated Infusion System
Markevicius V, Andrijauskas A, Navikas D, Svensen C, Porvaneckas N, Andriukaitis D, et al
ELEKTRONIKA IR ELEKTROTECHNIKA 2013;19(7):65-71

The maintenance and monitoring of perioperative blood volume
Iijima T, Brandstrup B, Rodhe P, Andrijauskas A, Svensen Ch
Perioperative medicine (London, England) 2013;2(1):9-

The use of a noninvasive hemoglobin monitor for volume kinetic analysis in an emergency room setting
Sjöstrand F, Rodhe P, Berglund E, Lundström N, Svensen C
Anesthesia and analgesia 2013;116(2):337-42

Preoperative ultrasound monitoring can reduce postoperative bladder distension: A randomized study
Joelsson-alm E, Ulfvarson J, Nyman Cr, Divander Mb, Svensen C
SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY 2012;46(2):84-90

[Leading anesthesiologist accused of scientific misconduct. We are not changing our protocols--yet]
Svensén C
Lakartidningen 2011;108(16-17):905-

[Swedish patients can receive better anesthesiologic care. Fluid therapy and oxygen administration in major bowel surgery are not optimal according to a questionnaire]
Cleaver B, Wogensen F, Svensén C
Lakartidningen 2011;108(40):1963-7

[A successful educational program for medical and nursing students. Interprofessional learning gives insights and strengthens team work]
Olivecrona C, Kärrlander S, Hylin U, Törnkvist H, Jonsson C, Svensén C
Lakartidningen 2010;107(3):113-5

End-tidal carbon dioxide monitoring during bag valve ventilation: the use of a new portable device
Lindstrom V, Svensen Ch, Meissl P, Tureson B, Castren M
SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE 2010;:49-

Hypoproteinemia does not alter plasma volume expansion in response to a 0.9% saline bolus in awake sheep
Brauer Ki, Brauer Lp, Prough Ds, Rodhe P, Hahn Rg, Traber Dl, et al
CRITICAL CARE MEDICINE 2010;38(10):2011-5

Modelling of peripheral fluid accumulation after a crystalloid bolus in female volunteers - a mathematical study
Rodhe P, Drobin D, Hahn Rg, Wennberg B, Lindahl C, Sjostrand F, et al
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE 2010;11(4):341-51

[Naval trauma surgery. Swedish challenge in an international operation]
Larsson H, Nilsson Ne, Ninn J, Svensén C
Lakartidningen 2010;107(13-14):914-5

Arteriovenous Differences in Plasma Dilution and the Distribution Kinetics of Lactated Ringer's Solution
Svensen Ch, Rodhe Pm, Olsson J, Borsheim E, Aarsland A, Hahn Rg
ANESTHESIA AND ANALGESIA 2009;108(1):128-33

[Helicopters in health care can solve the logistics and strengthen the competence]
Sundstrom K, Svensén C
Lakartidningen 2009;106(17):1182-5

Perioperative bladder distension: A prospective study
Joelsson-alm E, Nyman Cr, Lindholm C, Ulfvarson J, Svensen C
SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY 2009;43(1):58-62

Pharmacokinetic aspects of fluid therapy
Svensen Ch, Rodhe Pm, Prough Ds
Best practice & research. Clinical anaesthesiology 2009;23(2):213-24

A volume loading test for the detection of hypovolemia and dehydration
Hahn Rg, Andrijauskas A, Drobin D, Svensen C, Ivaskevicius J
MEDICINA-LITHUANIA 2008;44(12):953-9

Population volume kinetics predicts retention of 0.9% saline infused in awake and isoflurane-anesthetized volunteers
Norberg A, Hahn Rg, Li Hs, Olsson J, Prough Ds, Borsheim E, et al
ANESTHESIOLOGY 2007;107(1):24-32

Hemorrhage and operation cause a contraction of the extracellular space needing replacement - evidence and implications? A systematic review
Brandstrup B, Svensen C, Engquist A
SURGERY 2006;139(3):419-32

Intravascular fluid administration and hemodynamic performance during open abdominal surgery
Svensen Ch, Olsson J, Hahn Rg
ANESTHESIA AND ANALGESIA 2006;103(3):671-6

Isoflurane inhibits compensatory intravascular volume expansion after hemorrhage in sheep
Hahn Rg, Brauer L, Rodhe P, Svensen Ch, Prough Ds
ANESTHESIA AND ANALGESIA 2006;103(2):350-8

Perioperative fluid management
Prough Ds, Svensen Ch
ANESTHESIA AND ANALGESIA 2006;:84-91

Role of capillary filtration coefficient in volume expansion in healthy volunteers
Kinsky Mp, Prough Ds, Svensen C, Kramer Gc, Moore Ms
FASEB JOURNAL 2006;20(4):A708-A708

Optoacoustic monitoring of blood hemoglobin concentration: a pilot clinical study
Petrova Iy, Esenaliev Ro, Petrov Yy, Brecht Hpe, Svensen Ch, Olsson J, et al
OPTICS LETTERS 2005;30(13):1677-9

Sepsis produced by Pseudomonas bacteremia does not alter plasma volume expansion after 0.9% saline infusion in sheep
Svensen Ch, Clifton B, Brauer Ki, Olsson J, Uchida T, Traber Ld, et al
ANESTHESIA AND ANALGESIA 2005;101(3):835-42

Volume turnover kinetics of fluid shifts after hemorrhage, fluid infusion, and the combination of hemorrhage and fluid infusion in sheep
Norberg A, Brauer Ki, Prough Ds, Gabrielsson J, Hahn Rg, Uchida T, et al
ANESTHESIOLOGY 2005;102(5):985-94

Elimination rate constant describing clearance of infused fluid from plasma is independent of large infusion volumes of 0.9% saline in sheep
Svensen Ch, Brauer Kp, Hahn Rg, Uchida T, Traber Ld, Traber Dl, et al
ANESTHESIOLOGY 2004;101(3):666-74

Epidural anesthesia, hypotension, and changes in intravascular volume
Holte K, Foss Nb, Svensen C, Lund C, Madsen Jl, Kehlet H
ANESTHESIOLOGY 2004;100(2):281-6

The volume kinetics of acetated Ringer's solution during laparoscopic cholecystectomy
Olsson J, Svensen Ch, Hahn Rg
ANESTHESIA AND ANALGESIA 2004;99(6):1854-60

Vascular endothelial growth factor (VEGF) in plasma increases after hip surgery
Svensen Ch
JOURNAL OF CLINICAL ANESTHESIA 2004;16(6):435-9

Isoflurane but not mechanical ventilation promotes extravascular fluid accumulation during crystafloid volume loading
Connolly Cm, Kramer Gc, Hahn Rg, Chaisson Nf, Svensen Ch, Kirschner Ra, et al
ANESTHESIOLOGY 2003;98(3):670-81

Natriuresis and the extracellular volume expansion by hypertonic saline
Svensen Ch, Waldrop Ks, Edsberg L, Hahn Rg
JOURNAL OF SURGICAL RESEARCH 2003;113(1):6-12

Influence of rate and volume of infusion on the kinetics of 0.9% saline and 7.5% saline/6.0% dextran 70 in sheep
Brauer Lp, Svensen Ch, Hahn Rg, Kilicturgay S, Kramer Gc, Prough Ds
ANESTHESIA AND ANALGESIA 2002;95(6):1547-56

Lower dose of hypertonic saline dextran reduces the risk of lethal rebleeding in uncontrolled hemorrhage
Riddez L, Drobin D, Sjostrand F, Svensen C, Hahn Rg
SHOCK 2002;17(5):377-82

Perioperative fluid management
Prough Ds, Svensen C
ANESTHESIA AND ANALGESIA 2002;94(3):84-91

Volume kinetic analysis of the distribution of 0.9% saline in conscious versus isoflurane-anesthetized sheep
Brauer Ki, Svensen C, Hahn Rg, Traber Ld, Prough Ds
ANESTHESIOLOGY 2002;96(2):442-9

Effects of mechanical ventilation and inhalation anesthesia on the redistribution of intravenous fluid in sheep
Connolly C, Kramer Gc, Chaisson Nf, Kirschner Ra, Hastings Da, Hahn Rg, et al
CRITICAL CARE MEDICINE 2001;29(12):A84-A84

To bolus or not to bolus - is that the question?
Editorial Board, Kramer Gc, Svensen Ch, Prough Ds
CLINICAL SCIENCE 2001;101(2):181-3

Volume kinetics of intravenous fluid therapy in the prehospital setting
Svensén C, Sjöstrand F, Hahn Rg
Prehospital and disaster medicine 2001;16(1):9-13

Stability of the interstitial matrix after crystalloid fluid loading studied by volume kinetic analysis
Svensen C, Drobin D, Olsson J, Hahn Rg
BRITISH JOURNAL OF ANAESTHESIA 1999;82(4):496-502

The use of volume kinetics as a method to optimise fluid therapy
Svensen C
ACTA ANAESTHESIOLOGICA SCANDINAVICA 1999;43(9):969-969

[Volume kinetics--a new method to control intravenous fluid infusion]
Svensén C, Drobin D, Edsberg L, Ståhle L, Hahn R
Lakartidningen 1999;96(16):1969-70

Volume kinetics of Ringer solution after surgery for hip fracture
Svensen C, Ponzer S, Hahn Rg
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE 1999;46(2):133-41

Central and regional hemodynamics during acute hypovolemia and volume substitution in volunteers
Riddez L, Hahn Rg, Brismar B, Strandberg A, Svensen C, Hedenstierna G
CRITICAL CARE MEDICINE 1997;25(4):635-40

Plasma dilution and the rate of infusion of Ringer's solution
Hahn Rg, Svensen C
BRITISH JOURNAL OF ANAESTHESIA 1997;79(1):64-7

Volume kinetics of ringer solution, dextran 70, and hypertonic saline in male volunteers
Svensen C, Hahn Rg
ANESTHESIOLOGY 1997;87(2):204-12

Volume kinetics of Ringer solution during endotoxinemia in conscious rabbits
Svensen C, Hjelmqvist H, Hahn Rg
JOURNAL OF ENDOTOXIN RESEARCH 1997;4(6):425-430

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