Cecilia Dominguez

Publications
CV
Public outreach and news

Articles

Article: AUTOPHAGY. 2023;19(7):1952-1981

Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy.

Beccari S; Sierra-Torre V; Valero J; Pereira-Iglesias M; García-Zaballa M; Soria FN; De Las Heras-Garcia L; Carretero-Guillen A; Capetillo-Zarate E; Domercq M; Huguet PR; Ramonet D; Osman A; Han W; Dominguez C; Faust TE; Touzani O; Pampliega O; Boya P; Schafer D; Mariño G; Canet-Soulas E; Blomgren K; Plaza-Zabala A; Sierra A
Journal article: MOLECULAR PSYCHIATRY. 2021;26(1):1-2

Irradiation-induced changes in neural progenitor cells are reversed by lithium: Immature newborn dentate granule neurons display dendritic processes that are either tangential or parallel to the granule cell layer of the dentate gyrus of the hippocampus

Zanni G; Goto S; Fragopoulou AF; Gaudenzi G; Naidoo V; Di Martino E; Levy G; Dominguez CA; Dethlefsen O; Cedazo-Minguez A; Merino-Serrais P; Stamatakis A; Hermanson O; Blomgren K
Article: MOLECULAR PSYCHIATRY. 2021;26(1):322-340

Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition.

Zanni G; Goto S; Fragopoulou AF; Gaudenzi G; Naidoo V; Di Martino E; Levy G; Dominguez CA; Dethlefsen O; Cedazo-Minguez A; Merino-Serrais P; Stamatakis A; Hermanson O; Blomgren K
Article: NEUROSCIENCE. 2019;405:92-102

The Secretome of Microglia Regulate Neural Stem Cell Function.

Osman AM; Rodhe J; Shen X; Dominguez CA; Joseph B; Blomgren K
Article: ONCOTARGET. 2016;7(50):82305-82323

Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia.

Han W; Umekawa T; Zhou K; Zhang X-M; Ohshima M; Dominguez CA; Harris RA; Zhu C; Blomgren K
Article: JOURNAL OF NEUROINFLAMMATION. 2015;12:192

Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response.

Lindblom RPF; Berg A; Ström M; Aeinehband S; Dominguez CA; Al Nimer F; Abdelmagid N; Heinig M; Zelano J; Harnesk K; Hübner N; Nilsson B; Ekdahl KN; Diez M; Cullheim S; Piehl F
Article: MOLECULAR PAIN. 2014;10:78

Variability in C-type lectin receptors regulates neuropathic pain-like behavior after peripheral nerve injury.

Dominguez CA; Carlström KE; Zhang X-M; Al Nimer F; Lindblom RPF; Ortlieb Guerreiro-Cacais A; Piehl F
Article: JOURNAL OF IMMUNOLOGY. 2014;192(3):1138-1153

Unbiased expression mapping identifies a link between the complement and cholinergic systems in the rat central nervous system.

Lindblom RPF; Ström M; Heinig M; Al Nimer F; Aeinehband S; Berg A; Dominguez CA; Vijayaraghavan S; Zhang X-M; Harnesk K; Zelano J; Hübner N; Cullheim S; Darreh-Shori T; Diez M; Piehl F
Article: JOURNAL OF NEUROINFLAMMATION. 2013;10:60

Genetic variability in the rat Aplec C-type lectin gene cluster regulates lymphocyte trafficking and motor neuron survival after traumatic nerve root injury.

Lindblom RPF; Aeinehband S; Parsa R; Ström M; Al Nimer F; Zhang X-M; Dominguez CA; Flytzani S; Diez M; Piehl F
Article: PAIN. 2013;154(3):427-433

The DQB1 *03:02 HLA haplotype is associated with increased risk of chronic pain after inguinal hernia surgery and lumbar disc herniation.

Dominguez CA; Kalliomäki M; Gunnarsson U; Moen A; Sandblom G; Kockum I; Lavant E; Olsson T; Nyberg F; Rygh LJ; Røe C; Gjerstad J; Gordh T; Piehl F
Article: EUROPEAN JOURNAL OF PAIN. 2012;16(10):1368-1377

Genetic and sex influence on neuropathic pain-like behaviour after spinal cord injury in the rat.

Dominguez CA; Ström M; Gao T; Zhang L; Olsson T; Wiesenfeld-Hallin Z; Xu X-J; Piehl F
Article: GENDER MEDICINE. 2009;6 Suppl 2:225-234

Sex differences in the development of localized and spread mechanical hypersensitivity in rats after injury to the infraorbital or sciatic nerves to create a model for neuropathic pain.

Dominguez CA; Kouya PF; Wu W-P; Hao J-X; Xu X-J; Wiesenfeld-Hallin Z
Article: RESTORATIVE NEUROLOGY AND NEUROSCIENCE. 2009;27(4):307-321

Multipotent mesenchymal stromal cells attenuate chronic inflammation and injury-induced sensitivity to mechanical stimuli in experimental spinal cord injury.

Abrams MB; Dominguez C; Pernold K; Reger R; Wiesenfeld-Hallin Z; Olson L; Prockop D
Article: NEUROSCIENCE LETTERS. 2008;443(2):95-98

Contrasting genetic effects of major histocompatibility complex on ischemic peripheral nerve and spinal cord injury in female rats.

Dominguez CA; Lidman O; Olsson T; Wiesenfeld-Hallin Z; Piehl F; Xu X-J
Article: NEUROSCIENCE LETTERS. 2008;442(3):284-286

Both MHC and non-MHC genes regulate development of experimental neuropathic pain in rats.

Dominguez CA; Li L; Lidman O; Olsson T; Wiesenfeld-Hallin Z; Piehl F; Xu X-J
Article: PAIN. 2008;136(3):313-319

Genetic analysis of neuropathic pain-like behavior following peripheral nerve injury suggests a role of the major histocompatibility complex in development of allodynia.

Dominguez CA; Lidman O; Hao J-X; Diez M; Tuncel J; Olsson T; Wiesenfeld-Hallin Z; Piehl F; Xu X-J
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2007;26(5):1118-1127

Recovery from spinal cord injury differs between rat strains in a major histocompatibility complex-independent manner.

Birdsall Abrams M; Josephson A; Dominguez C; Oberg J; Diez M; Spenger C; Olson L; Piehl F; Lidman O
Article: JOURNAL OF NEUROSCIENCE. 2005;25(37):8432-8438

Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons.

Andersson M; Usiello A; Borgkvist A; Pozzi L; Dominguez C; Fienberg AA; Svenningsson P; Fredholm BB; Borrelli E; Greengard P; Fisone G

All other publications

Preprint: RESEARCH SQUARE. 2023

Microglial depletion and repopulation did not affect hippocampal neurogenesis after whole brain irradiation

Zhou K; Zisiadis GA; Havermans M; Dominguez C; Ohshima M; Rodrigues CFD; Blomgren K
Preprint: BIORXIV. 2021

Microglial phagocytosis dysfunction during stroke is prevented by rapamycin

Beccari S; Sierra-Torre V; Valero J; García-Zaballa M; Carretero-Guillen A; Capetillo-Zarate E; Domercq M; Huguet P; Ramonet D; Osman A; Han W; Dominguez C; Faust T; Touzani O; Boya P; Schafer D; Mariño G; Canet-Soulas E; Blomgren K; Plaza-Zabala A; Sierra A
Conference publication: GLIA. 2017;65:E330

Ischemia/stroke rapidly impairs microglial phagocytosis in vivo

Galeano MSB; Umekawa T; Osman A; Han W; Dominguez C; Blomgren K; Sierra A

Employments

Senior Lab Manager, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2023-
Senior Lab Manager, Department of Women's and Children's Health, Karolinska Institutet, 2019-2023

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2008

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