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Björn Pasternak

Senior researcher

Visiting address : Eugeniahemmet, T2, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm, Sweden
Postal address : Department of Medicine, Solna (MedS), K2, Group J Askling, Eugeniahemmet, T2, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm, Sweden
Delivery address : Eugeniahemmet, T2, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm, Sweden

Education

2007   MD, Linköping University, Sweden

2008   PhD, Linköping University, Sweden

Research description

Thriving on substantial expertise in large-scale register studies of adverse drug effects, we have the overall objective of using high-quality epidemiology to help inform evidence-based decisions in clinical practice. We are currently launching research programs in pediatric pharmacoepidemiology and the area of expedited assessment of current drug safety concerns. My group’s scope is not limited to one single disease entity or therapeutic area; rather, we are in a constant process of seeking out and addressing emerging drug safety concerns with implications for clinical practice.  

 

I have recently joined Karolinska Institutet following and am building up a research group. Young academics as well as seasoned researchers looking to pursue research that aims to advance the safe use of medications in clinical practice are welcome to contact us!

 

Group members

 

Our research is funded by

  • Swedish Research Council
  • Swedish Cancer Society
  • Swedish Heart-Lung Foundation
  • Novo Nordisk Foundation
  • Karolinska Institutet Funds
  • Stiftelsen Frimurare Barnhuset
  • Åke Wibergs Stiftelse

 

Selected publications

Association Between Use of Oral Fluconazole During Pregnancy and Risk of Spontaneous Abortion and Stillbirth
Molgaard-nielsen D, Svanstrom H, Melbye M, Hviid A, Pasternak B
JAMA 2016;315(1):58-67

 

Quadrivalent HPV vaccination and risk of multiple sclerosis and other demyelinating diseases of the central nervous system
Scheller Nm, Svanstrom H, Pasternak B, Arnheim-dahlstrom L, Sundstrom K, Fink K, et al
JAMA 2015;313(1):54-61

 

Quadrivalent human papillomavirus vaccine and the risk of venous thromboembolism
Scheller Nm, Pasternak B, Svanstrom H, Hviid A
JAMA 2014;312(2):187-8

 

Association between tumor necrosis factor-α antagonists and risk of cancer in patients with inflammatory bowel disease
Nyboe Andersen N, Pasternak B, Basit S, Andersson M, Svanstrom H, Caspersen S, et al
JAMA 2014;311(23):2406-13

 

Common variants associated with general and MMR vaccine-related febrile seizures
Feenstra B, Pasternak B, Geller F, Carstensen L, Wang T, Huang F, et al
Nature genetics 2014;46(12):1274-82

 

Use of oral fluconazole during pregnancy and the risk of birth defects
Molgaard-nielsen D, Pasternak B, Hviid A
The New England journal of medicine 2013;369(9):830-9

 

Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism
Hviid A, Melbye M, Pasternak B
The New England journal of medicine 2013;369(25):2406-15

 

Use of azithromycin and death from cardiovascular causes
Svanstrom H, Pasternak B, Hviid A
The New England journal of medicine 2013;368(18):1704-12

 

Association between oral fluoroquinolone use and retinal detachment
Pasternak B, Svanstrom H, Melbye M, Hviid A
JAMA 2013;310(20):2184-90

Metoclopramide in pregnancy and risk of major congenital malformations and fetal death
Pasternak B, Svanstrom H, Molgaard-nielsen D, Melbye M, Hviid A
JAMA 2013;310(15):1601-11

 

Ondansetron in pregnancy and risk of adverse fetal outcomes
Pasternak B, Svanstrom H, Hviid A
The New England journal of medicine 2013;368(9):814-23

 

Risk of adverse fetal outcomes following administration of a pandemic influenza A(H1N1) vaccine during pregnancy
Pasternak B, Svanstrom H, Molgaard-nielsen D, Krause Tg, Emborg Hd, Melbye M, et al
JAMA 2012;308(2):165-74

 

Vaccination against pandemic A/H1N1 2009 influenza in pregnancy and risk of fetal death: cohort study in Denmark
Pasternak B, Svanstrom H, Molgaard-nielsen D, Krause Tg, Emborg Hd, Melbye M, et al
BMJ (Clinical research ed.) 2012;344():e2794-

 

Association of treatment with losartan vs candesartan and mortality among patients with heart failure
Svanstrom H, Pasternak B, Hviid A
JAMA 2012;307(14):1506-12

 

Use of acyclovir, valacyclovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects
Pasternak B, Hviid A
JAMA 2010;304(8):859-66

 

Use of proton-pump inhibitors in early pregnancy and the risk of birth defects
Pasternak B, Hviid A
The New England journal of medicine 2010;363(22):2114-23