Arne Lindqvist

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Articles

Article: MOLECULAR CELL. 2021;81(24):5007-5024.e9

Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1.

Wiegard A; Kuzin V; Cameron DP; Grosser J; Ceribelli M; Mehmood R; Ballarino R; Valant F; Grochowski R; Karabogdan I; Crosetto N; Lindqvist A; Bizard AH; Kouzine F; Natsume T; Baranello L
Article: LIFE SCIENCE ALLIANCE. 2021;4(3):e202000980

Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1.

Silva Cascales H; Burdova K; Middleton A; Kuzin V; Müllers E; Stoy H; Baranello L; Macurek L; Lindqvist A
Article: CELLS. 2020;9(9):E2126-2126

FRET-Based Sorting of Live Cells Reveals Shifted Balance between PLK1 and CDK1 Activities During Checkpoint Recovery.

Lafranchi L; Müllers E; Rutishauser D; Lindqvist A
Article: NUCLEIC ACIDS RESEARCH. 2020;48(10):5777-5787

Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers.

Verheyen T; Fang T; Lindenhofer D; Wang Y; Akopyan K; Lindqvist A; Högberg B; Teixeira AI
Article: CELL CHEMICAL BIOLOGY. 2019;26(10):1436-1449.e5

Neutralization of the Positive Charges on Histone Tails by RNA Promotes an Open Chromatin Structure.

Dueva R; Akopyan K; Pederiva C; Trevisan D; Dhanjal S; Lindqvist A; Farnebo M
Article: SCIENTIFIC REPORTS. 2019;9(1):13758

The human long non-coding RNA gene RMRP has pleiotropic effects and regulates cell-cycle progression at G2.

Vakkilainen S; Skoog T; Einarsdottir E; Middleton A; Pekkinen M; Öhman T; Katayama S; Krjutškov K; Kovanen PE; Varjosalo M; Lindqvist A; Kere J; Mäkitie O
Article: CELL REPORTS. 2019;26(7):1691-1700.e5

Mapping Metabolic Events in the Cancer Cell Cycle Reveals Arginine Catabolism in the Committed SG2M Phase.

Roci I; Watrous JD; Lagerborg KA; Lafranchi L; Lindqvist A; Jain M; Nilsson R
Article: MOLECULAR CELL. 2018;71(1):117-128.e3

DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.

Lemmens B; Hegarat N; Akopyan K; Sala-Gaston J; Bartek J; Hochegger H; Lindqvist A
Article: EMBO JOURNAL. 2017;36(14):2161-2176

ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.

Jaiswal H; Benada J; Müllers E; Akopyan K; Burdova K; Koolmeister T; Helleday T; Medema RH; Macurek L; Lindqvist A
Article: AGING CELL. 2017;16(3):575-584

Residual Cdk1/2 activity after DNA damage promotes senescence.

Müllers E; Silva Cascales H; Burdova K; Macurek L; Lindqvist A
Article: STEM CELL REPORTS. 2016;6(5):643-651

Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells.

Braune E-B; Tsoi YL; Phoon YP; Landor S; Silva Cascales H; Ramsköld D; Deng Q; Lindqvist A; Lian X; Sahlgren C; Jin S-B; Lendahl U
Article: METHODS IN MOLECULAR BIOLOGY. 2016;1342:173-183

Cell Cycle Dynamics of Proteins and Post-translational Modifications Using Quantitative Immunofluorescence.

Akopyan K; Lindqvist A; Müllers E
Article: FRONTIERS IN GENETICS. 2015;6:63

Bystander communication and cell cycle decisions after DNA damage.

Jaiswal H; Lindqvist A
Article: FRONTIERS IN ONCOLOGY. 2015;5:132

Spatial Separation of Plk1 Phosphorylation and Activity.

Bruinsma W; Aprelia M; Kool J; Macurek L; Lindqvist A; Medema RH
Article: PLOS GENETICS. 2014;10(10):e1004680

The chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement.

Jeppsson K; Carlborg KK; Nakato R; Berta DG; Lilienthal I; Kanno T; Lindqvist A; Brink MC; Dantuma NP; Katou Y; Shirahige K; Sjögren C
Article: ONCOTARGET. 2014;5(18):8379-8392

Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism.

Waraky A; Akopyan K; Parrow V; Strömberg T; Axelson M; Abrahmsén L; Lindqvist A; Larsson O; Aleem E
Article: CELL CYCLE. 2014;13(17):2733-2743

Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase.

Müllers E; Silva Cascales H; Jaiswal H; Saurin AT; Lindqvist A
Article: CELL DEATH & DISEASE. 2014;5(5):e1235

Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2.

Peng X; Mandal PK; Kaminskyy VO; Lindqvist A; Conrad M; Arnér ESJ
Article: MOLECULAR CANCER THERAPEUTICS. 2014;13(5):1054-1066

Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na.

Mäki-Jouppila JHE; Laine LJ; Rehnberg J; Narvi E; Tiikkainen P; Hukasova E; Halonen P; Lindqvist A; Kallio L; Poso A; Kallio MJ
Article: MOLECULAR CELL. 2014;53(5):843-853

Assessing kinetics from fixed cells reveals activation of the mitotic entry network at the S/G2 transition.

Akopyan K; Silva Cascales H; Hukasova E; Saurin AT; Müllers E; Jaiswal H; Hollman DAA; Kops GJPL; Medema RH; Lindqvist A
Article: JOURNAL OF CELL SCIENCE. 2014;127(Pt 4):801-811

Bora and Aurora-A continue to activate Plk1 in mitosis.

Bruinsma W; Macurek L; Freire R; Lindqvist A; Medema RH
Article: CELL CYCLE. 2014;13(11):1727-1736

Phosphorylation-mediated stabilization of Bora in mitosis coordinates Plx1/Plk1 and Cdk1 oscillations.

Feine O; Hukasova E; Bruinsma W; Freire R; Fainsod A; Gannon J; Mahbubani HM; Lindqvist A; Brandeis M
Article: CELL CYCLE. 2014;13(7):1162-1170

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

Tame MA; Raaijmakers JA; van den Broek B; Lindqvist A; Jalink K; Medema RH
Article: CELL CYCLE. 2013;12(2):251-262

Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis.

Macurek L; Benada J; Müllers E; Halim VA; Krejčíková K; Burdová K; Pecháčková S; Hodný Z; Lindqvist A; Medema RH; Bartek J
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2012;(59):e3410

Monitoring kinase and phosphatase activities through the cell cycle by ratiometric FRET.

Hukasova E; Silva Cascales H; Kumar SR; Lindqvist A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;417(4):1248-1253

Functional characterization of the pleckstrin homology domain of a cellulose synthase from the oomycete Saprolegnia monoica.

Fugelstad J; Brown C; Hukasova E; Sundqvist G; Lindqvist A; Bulone V
Article: ONCOGENE. 2010;29(15):2281-2291

Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition.

Macůrek L; Lindqvist A; Voets O; Kool J; Vos HR; Medema RH
Article: PLOS BIOLOGY. 2010;8(4):e1000350

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry.

Splinter D; Tanenbaum ME; Lindqvist A; Jaarsma D; Flotho A; Yu KL; Grigoriev I; Engelsma D; Haasdijk ED; Keijzer N; Demmers J; Fornerod M; Melchior F; Hoogenraad CC; Medema RH; Akhmanova A
Article: EMBO JOURNAL. 2009;28(20):3196-3206

Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression.

Lindqvist A; de Bruijn M; Macurek L; Brás A; Mensinga A; Bruinsma W; Voets O; Kranenburg O; Medema RH
Article: NATURE. 2008;455(7209):119-U88

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery.

Macůrek L; Lindqvist A; Lim D; Lampson MA; Klompmaker R; Freire R; Clouin C; Taylor SS; Yaffe MB; Medema RH
Article: PLOS BIOLOGY. 2007;5(5):e123-1137

Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression.

Lindqvist A; van Zon W; Karlsson Rosenthal C; Wolthuis RMF
Article: JOURNAL OF CELL BIOLOGY. 2005;171(1):35-45

Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome.

Lindqvist A; Källström H; Lundgren A; Barsoum E; Rosenthal CK
Article: EXPERIMENTAL CELL RESEARCH. 2005;303(1):89-100

Cdc25A localisation and shuttling: characterisation of sequences mediating nuclear export and import.

Källström H; Lindqvist A; Pospisil V; Lundgren A; Rosenthal CK
Article: JOURNAL OF CELL SCIENCE. 2004;117(Pt 21):4979-4990

Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress.

Lindqvist A; Källström H; Karlsson Rosenthal C
Article: MOLECULAR MICROBIOLOGY. 2001;42(5):1179-1188

Distribution of the Escherichia coli structural maintenance of chromosomes (SMC)-like protein MukB in the cell.

den Blaauwen T; Lindqvist A; Löwe J; Nanninga N
Article: ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY. 2000;78(1):23-31

Roles of respiratory oxidases in protecting Escherichia coli K12 from oxidative stress.

Lindqvist A; Membrillo-Hernańdez J; Poole RK; Cook GM
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All other publications

Book chapter: BIOMOLECULAR INTERACTIONS, PT A. 2024;p. 187-197

Using an ImageJ-based script to detect replication stress and associated cell cycle exit from G2 phase by fluorescence microscopy.

Lindqvist A; Hao Z; Akopyan K
Review: JOURNAL OF CELL BIOLOGY. 2019;218(12):3892-3902

DNA replication and mitotic entry: A brake model for cell cycle progression.

Lemmens B; Lindqvist A
Editorial comment: AGING-US. 2017;9(10):2022-2023

How the cell cycle enforces senescence.

Silva Cascales H; Müllers E; Lindqvist A
Review: TRENDS IN BIOCHEMICAL SCIENCES. 2011;36(11):578-584

Boosting and suppressing mitotic phosphorylation.

Medema RH; Lindqvist A
Editorial comment: JOURNAL OF CELL BIOLOGY. 2010;189(2):197-199

Cyclin B-Cdk1 activates its own pump to get into the nucleus.

Lindqvist A
Review: CANCER RESEARCH. 2009;69(11):4555-4558

Aurora-A and hBora join the game of Polo.

Macurek L; Lindqvist A; Medema RH
Review: JOURNAL OF CELL BIOLOGY. 2009;185(2):193-202

The decision to enter mitosis: feedback and redundancy in the mitotic entry network.

Lindqvist A; Rodríguez-Bravo V; Medema RH

Employments

Principal Researcher, Department of Cell and Molecular Biology, Karolinska Institutet, 2022-

Degrees and Education

Docent, Karolinska Institutet, 2016
Doctor Of Philosophy, Department of Cell and Molecular Biology, Karolinska Institutet, 2005

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