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Antonio Gigliotti Rothfuchs

Senior researcher

Visiting address : Nobels Väg 16 171 77 Stockholm, Sweden
Postal address : Department of Microbiology, Tumor and Cell Biology (MTC), C1, Martin Rottenberg group, Box 280 171 77 Stockholm, Sweden
Delivery address : Nobels Väg 16 171 77 Stockholm, Sweden

Publications

A CFSE-based Assay to Study the Migration of Murine Skin Dendritic Cells into Draining Lymph Nodes During Infection with Mycobacterium bovis Bacille Calmette-Guérin
Bollampalli Vp, Nylén S, Rothfuchs Ag
Journal of visualized experiments : JoVE 2016;(116):-

Chronic Gastrointestinal Nematode Infection Mutes Immune Responses to Mycobacterial Infection Distal to the Gut
Obieglo K, Feng X, Bollampalli Vp, Dellacasa-lindberg I, Classon C, Österblad M, et al
Journal of immunology (Baltimore, Md. : 1950) 2016;196(5):2262-71

BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAMlow CD11bhigh Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming
Bollampalli Vp, Harumi Yamashiro L, Feng X, Bierschenk D, Gao Y, Blom H, et al
PLoS pathogens 2015;11(10):e1005206-

Nucleotide-binding oligomerization domain-2 (NOD2) regulates type-1 cytokine responses to Mycobacterium avium but is not required for host control of infection
Carvalho Nb, Oliveira Fs, Marinho Fa, De Almeida La, Fahel Js, Báfica A, et al
Microbes and infection 2015;17(5):337-44

IL-10 Limits Parasite Burden and Protects against Fatal Myocarditis in a Mouse Model of Trypanosoma cruzi Infection
Roffe E, Rothfuchs Ag, Santiago Hc, Marino Apmp, Ribeiro-gomes Fl, Eckhaus M, et al
JOURNAL OF IMMUNOLOGY 2012;188(2):649-60

Mannose-Binding Lectin Regulates Host Resistance and Pathology during Experimental Infection with Trypanosoma cruzi
Rothfuchs Ag, Roffe E, Gibson A, Cheever Aw, Ezekowitz Rab, Takahashi K, et al
PLOS ONE 2012;7(11):e47835-

Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas
Egen Jg, Rothfuchs Ag, Feng Cg, Horwitz Ma, Sher A, Germain Rn
IMMUNITY 2011;34(5):807-19

The Syk/CARD9-coupled receptor Dectin-1 is not required for host resistance to Mycobacterium tuberculosis in mice
Marakalala Mj, Guler R, Matika L, Murray G, Jacobs M, Brombacher F, et al
MICROBES AND INFECTION 2011;13(2):198-201

Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium
Min-oo G, Ayi K, Bongfen Se, Tam M, Radovanovic I, Gauthier S, et al
EXPERIMENTAL PARASITOLOGY 2010;125(4):315-24

Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population
Antonelli Lrv, Rothfuchs Ag, Goncalves R, Roffe E, Cheever Aw, Bafica A, et al
JOURNAL OF CLINICAL INVESTIGATION 2010;120(5):1674-82

In Situ IL-12/23p40 Production during Mycobacterial Infection Is Sustained by CD11b(high) Dendritic Cells Localized in Tissue Sites Distinct from Those Harboring Bacilli
Rothfuchs Ag, Egen Jg, Feng Cg, Antonelli Lrv, Bafica A, Winter N, et al
JOURNAL OF IMMUNOLOGY 2009;182(11):6915-25

Macrophage and T cell dynamics during the development and disintegration of mycobacterial Granulomas
Egen Jg, Rothfuchs Ag, Feng Cg, Winter N, Sher A, Germain Rn
IMMUNITY 2008;28(2):271-84

Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein
Soehnlein O, Oehmcke S, Ma X, Rothfuchs Ag, Frithiof R, Van Rooijen N, et al
EUROPEAN RESPIRATORY JOURNAL 2008;32(2):405-12

Neutrophil secretion products pave the way for inflammatory monocytes
Soehnlein O, Zernecke A, Eriksson Ee, Rothfuchs Ag, Pham Ct, Herwald H, et al
BLOOD 2008;112(4):1461-71

Dectin-1 interaction with mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells
Rothfuchs Ag, Bafica A, Feng Cg, Egen Jg, Williams Dl, Brown Gd, et al
JOURNAL OF IMMUNOLOGY 2007;179(6):3463-71

NK cell-derived IFN-gamma differentially regulates innate resistance and neutrophil response in T cell-deficient hosts infected with Mycobacterium tuberculosis
Feng Cg, Kaviratne M, Rothfuchs Ag, Cheever A, Hieny S, Young Ha, et al
JOURNAL OF IMMUNOLOGY 2006;177(10):7086-93

STAT1 regulates IFN-alpha beta- and IFN-gamma-dependent control of infection with Chlamydia pneumoniae by nonhemopoietic cells
Rothfuchs Ag, Trumstedt C, Mattei F, Schiavoni G, Hidmark A, Wigzell H, et al
JOURNAL OF IMMUNOLOGY 2006;176(11):6982-90

Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signaling
Rothfuchs Ag, Trumstedt C, Wigzell H, Rottenberg Me
JOURNAL OF IMMUNOLOGY 2004;172(10):6345-53

Macrophages, CD4(+) or CD8(+) cells are each sufficient for protection against Chlamydia pneumoniae infection through their ability to secrete IFN-gamma
Rothfuchs Ag, Kreuger Mr, Wigzell H, Rottenberg Me
JOURNAL OF IMMUNOLOGY 2004;172(4):2407-15

CD44-regulated intracellular proliferation of Listeria monocytogenes
Eriksson E, Dons L, Rothfuchs Ag, Heldin P, Wigzell H, Rottenberg Me
INFECTION AND IMMUNITY 2003;71(7):4102-11

The role of IFN-gamma in the outcome of chlamydial infection
Rottenberg Me, Gigliotti-rothfuchs A, Wigzell H
CURRENT OPINION IN IMMUNOLOGY 2002;14(4):444-51

Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: Cytokine requirements for the induction and maintenance of intestinal inflammation
Kullberg Mc, Rothfuchs Ag, Jankovic D, Caspar P, Wynn Ta, Gorelick Pl, et al
INFECTION AND IMMUNITY 2001;69(7):4232-41

IFN-alpha beta-dependent, IFN-gamma secretion by bone-marrow-derived macrophages controls an intracellular bacterial infection
Rothfuchs Ag, Gigliotti D, Palmblad K, Andersson U, Wigzell H, Rottenberg Me
JOURNAL OF IMMUNOLOGY 2001;167(11):6453-61

Regulation and role of IFN-gamma in the innate resistance to infection with Chlamydia pneumoniae
Rottenberg Me, Rothfuchs Ag, Gigliotti D, Ceausu M, Une C, Levitsky V, et al
JOURNAL OF IMMUNOLOGY 2000;164(9):4812-8

Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice
Rottenberg Me, Rothfuchs Acg, Gigliotti D, Svanholm C, Bandholtz L, Wigzell H
JOURNAL OF IMMUNOLOGY 1999;162(5):2829-36

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