Antonio Gigliotti Rothfuchs

Antonio Gigliotti Rothfuchs

Principal Researcher | Docent
Telephone: +46852485252
Visiting address: Solnavägen 9, C9, 17165 Solna
Postal address: C1 Mikrobiologi, tumör- och cellbiologi, C1 MTC Rothfuchs, 171 77 Stockholm

About me

  • My laboratory studies the immunology and aerobiology of mycobacteria. We
    employ a variety of tailored methods adapted to Biosafety Level 3 to
    investigate Mycobacterium tuberculosis in aerosols.
    I have more than 15 years of research experience with intracellular
    pathogens, primarily Mycobacterium species, under Biosafety Level 2 (BSL2)
    and BSL3 and in mouse models. I am Chairman of the Biosafety Committee at
    Karolinska Institutet and help oversee KI's regulations on biosafety,
    containment work in different biosafety levels and the handling of
    genetically-modified microorganisms. I am also Director of the BSL3 core
    facility at Biomedicum which supports research on risk group 3 bacteria,
    parasites and viruses.

    Associate Professor of Immunology (Docent), Karolinska Institutet. 2014
    Doctor of Medical Science (PhD) in Immunobiology, Karolinska Institutet. 2004
    Master of Medical Science with a Major in Biomedicine, Karolinska Institutet. 1999

Research

  • My laboratory does basic research on the immunology and infection biology of
    mycobacteria. We are particularly interested in the aerobiology of
    Mycobacterium tuberculosis and in techniques to capture and analyze
    pathogens in the air. We have developed an aerobiology platform in BSL3 where
    highly-pathogenic microorganisms can be safely and experimentally
    aerosolized, collected using different air samplers and detected by different
    analytical methods. We are using this platform to investigate the performance
    of an electrostatic air sampler for M. tuberculosis developed in the lab
  • to investigate biosafety and sampling performance of commercial samplers
  • and
    to study the effects of aerosol transport on the survival, infectivity and
    immune response of M. tuberculosis and SARS-CoV-2.

Teaching

Articles

All other publications

Employments

  • Principal Researcher, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2022-

Degrees and Education

  • Docent, Karolinska Institutet, 2014
  • Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2004
  • Master Of Medical Science, Karolinska Institutet, 1999

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