Anna-Klara Rundlöf

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Articles

Article: ANTIOXIDANTS & REDOX SIGNALING. 2013;18(7):795-799

Is trichloroacetic acid an insufficient sample quencher of redox reactions?

Curbo S; Reiser K; Rundlöf A-K; Karlsson A; Lundberg M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013;430(1):90-94

Simvastatin inhibits the core promoter of the TXNRD1 gene and lowers cellular TrxR activity in HepG2 cells.

Ekström L; Johansson M; Monostory K; Rundlöf A-K; Arnér ESJ; Björkhem-Bergman L
Article: BIOCHEMICAL PHARMACOLOGY. 2012;84(5):712-721

Inhibition of sphingosine kinase 1 enhances cytotoxicity, ceramide levels and ROS formation in liver cancer cells treated with selenite.

Chatzakos V; Rundlöf AK; Ahmed D; de Verdier PJ; Flygare J
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2011;50(11):1620-1629

Interaction of selenite and tellurite with thiol-dependent redox enzymes: Kinetics and mitochondrial implications.

Rigobello MP; Folda A; Citta A; Scutari G; Gandin V; Fernandes AP; Rundlöf A-K; Marzano C; Björnstedt M; Bindoli A
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2009;47(6):710-721

Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift.

Rigobello MP; Gandin V; Folda A; Rundlöf A-K; Fernandes AP; Bindoli A; Marzano C; Björnstedt M
Article: CANCER LETTERS. 2009;282(1):116-123

Selenite is a potent cytotoxic agent for human primary AML cells.

Olm E; Jönsson-Videsäter K; Ribera-Cortada I; Fernandes AP; Eriksson LC; Lehmann S; Rundlöf A-K; Paul C; Björnstedt M
Article: HISTOPATHOLOGY. 2009;55(3):313-320

Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation.

Fernandes AP; Capitanio A; Selenius M; Brodin O; Rundlöf A-K; Björnstedt M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(27):11400-11405

Extracellular thiol-assisted selenium uptake dependent on the x(c)- cystine transporter explains the cancer-specific cytotoxicity of selenite.

Olm E; Fernandes AP; Hebert C; Rundlöf A-K; Larsen EH; Danielsson O; Björnstedt M
Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2009;28(1):92

Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure.

Nilsonne G; Olm E; Szulkin A; Mundt F; Stein A; Kocic B; Rundlöf A-K; Fernandes AP; Björnstedt M; Dobra K
Article: FEBS JOURNAL. 2009;276(2):532-540

Effects of the antioxidant Pycnogenol on cellular redox systems in U1285 human lung carcinoma cells.

Gandin V; Nyström C; Rundlöf A-K; Jönsson-Videsäter K; Schönlau F; Hörkkö J; Björnstedt M; Fernandes AP
Article: BIOCHEMICAL PHARMACOLOGY. 2008;75(11):2092-2099

Treatment of lung cancer cells with cytotoxic levels of sodium selenite: effects on the thioredoxin system.

Selenius M; Fernandes AP; Brodin O; Björnstedt M; Rundlöf A-K
Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2007;459(2):178-188

Differential regulation of expression of cytosolic and mitochondrial thioredoxin reductase in rat liver and kidney.

Crosley LK; Méplan C; Nicol F; Rundlöf AK; Arnér ESJ; Hesketh JE; Arthur JR
Article: DIFFERENTIATION. 2007;75(2):123-132

Quantification of alternative mRNA species and identification of thioredoxin reductase 1 isoforms in human tumor cells.

Rundlöf A-K; Fernandes AP; Selenius M; Babic M; Shariatgorji M; Nilsonne G; Ilag LL; Dobra K; Björnstedt M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2006;41(6):874-885

Selenite induces apoptosis in sarcomatoid malignant mesothelioma cells through oxidative stress.

Nilsonne G; Sun X; Nyström C; Rundlöf A-K; Potamitou Fernandes A; Björnstedt M; Dobra K
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2004;37(1):71-85

Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins.

Furman C; Rundlöf A-K; Larigauderie G; Jaye M; Bricca G; Copin C; Kandoussi AM; Fruchart J-C; Arnér ESJ; Rouis M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2004;36(5):641-656

Evidence for intriguingly complex transcription of human thioredoxin reductase 1.

Rundlöf A-K; Janard M; Miranda-Vizuete A; Arnér ESJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(32):30542-30551

The core promoter of human thioredoxin reductase 1: cloning, transcriptional activity, and Oct-1, Sp1, and Sp3 binding reveal a housekeeping-type promoter for the AU-rich element-regulated gene.

Rundlöf AK; Carlsten M; Arnér ES
Article: BIOCHEMICAL JOURNAL. 2000;347 Pt 3(Pt 3):661-668

Prominent expression of the selenoprotein thioredoxin reductase in the medullary rays of the rat kidney and thioredoxin reductase mRNA variants differing at the 5' untranslated region.

Rundlöf AK; Carlsten M; Giacobini MM; Arnér ES
Article: MOLECULAR GENETICS AND GENOMICS. 1999;260(6):603-607

Either of the chromosomal tuf genes of E. coli K-12 can be deleted without loss of cell viability.

Zuurmond AM; Rundlöf AK; Kraal B

All other publications

Review: ANTIOXIDANTS & REDOX SIGNALING. 2010;12(7):867-880

Selenium and the selenoprotein thioredoxin reductase in the prevention, treatment and diagnostics of cancer.

Selenius M; Rundlöf A-K; Olm E; Fernandes AP; Björnstedt M
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2007;5(4):369

Selenite mediated cytotoxcicity in human lung cancer and the role of thioredoxin reductase 1

Fernandes AP; Selenius M; Capitanio A; Brodin O; Bjornstedt M; Rundlof AK
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2007;5(4):347

Selenite is a superior cytotoxic agent to human primary leukemia cells

Olm E; Jonsson-Videsaler K; Rundlof AK; Fernandes AP; Ribera I; Eriksson L; Paul C; Bjornstedt M
Meeting abstract: LUNG CANCER. 2006;54:S52

Targeting thioredoxin reductase -: a possible new treatment for malignant mesothelioma

Nilsonne G; Stein A; Rundloef A-K; Fernandes AP; Bjoernstedt M; Hjerpe A; Dobra K
Review: ANTIOXIDANTS & REDOX SIGNALING. 2004;6(1):41-52

Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events.

Rundlöf A-K; Arnér ESJ
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):291

The thioredoxin reductase/thioredoxin system is upregulated in atherosclerotic plaques:: Specific induction in human macrophages by oxidized low density lipoproteins

Furman C; Rundlöf AK; Jaye M; Searfoss G; Yue KT; Larigauderie G; Copin C; Kandoussi AM; Fruchart JC; Arnér ESJ; Rouis M

Employments

Senior Lecturer, Teaching and learning, Karolinska Institutet, 2023-
Senior Lecturer, Department of Laboratory Medicine, Karolinska Institutet, 2011-2023

Degrees and Education

Docent, Karolinska Institutet, 2012
Doctor Of Philosophy, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2003

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