Anders Mälarstig

Article: NATURE COMMUNICATIONS. 2023;14(1):7680

Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation.

Mälarstig A; Grassmann F; Dahl L; Dimitriou M; McLeod D; Gabrielson M; Smith-Byrne K; Thomas CE; Huang T-H; Forsberg SKG; Eriksson P; Ulfstedt M; Johansson M; Sokolov AV; Schiöth HB; Hall P; Schwenk JM; Czene K; Hedman ÅK

Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(5):1777-1788

Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes: Meta-Analyses and Mendelian Randomization Analyses.

Lind L; Gigante B; Borné Y; Feldreich T; Leppert J; Hedberg P; Östgren CJ; Nyström FH; Sundström J; Ärnlöv J; Baldassarre D; Tremoli E; Veglia F; Hamsten A; O'Donnell CJ; Franceschini N; Orho-Melander M; Nilsson J; Melander O; Engström G; Mälarstig A

Article: SCIENTIFIC REPORTS. 2021;11(1):1965

Accelerated inflammatory aging in Alzheimer's disease and its relation to amyloid, tau, and cognition.

Cullen NC; Mälarstig AN; Stomrud E; Hansson O; Mattsson-Carlgren N

Article: GENES. 2020;11(11):E1243-1243

Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study.

Castaldo L; Laguzzi F; Strawbridge RJ; Baldassarre D; Veglia F; Vigo L; Tremoli E; de Faire U; Eriksson P; Smit AJ; Aubrecht J; Leander K; Pirro M; Giral P; Ritieni A; Di Minno G; Mälarstig A; Gigante B

Article: NATURE METABOLISM. 2020;2(10):1135-1148

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.

Folkersen L; Gustafsson S; Wang Q; Hansen DH; Hedman ÅK; Schork A; Page K; Zhernakova DV; Wu Y; Peters J; Eriksson N; Bergen SE; Boutin TS; Bretherick AD; Enroth S; Kalnapenkis A; Gådin JR; Suur BE; Chen Y; Matic L; Gale JD; Lee J; Zhang W; Quazi A; Ala-Korpela M; Choi SH; Claringbould A; Danesh J; Davey Smith G; de Masi F; Elmståhl S; Engström G; Fauman E; Fernandez C; Franke L; Franks PW; Giedraitis V; Haley C; Hamsten A; Ingason A; Johansson Å; Joshi PK; Lind L; Lindgren CM; Lubitz S; Palmer T; Macdonald-Dunlop E; Magnusson M; Melander O; Michaelsson K; Morris AP; Mägi R; Nagle MW; Nilsson PM; Nilsson J; Orho-Melander M; Polasek O; Prins B; Pålsson E; Qi T; Sjögren M; Sundström J; Surendran P; Võsa U; Werge T; Wernersson R; Westra H-J; Yang J; Zhernakova A; Ärnlöv J; Fu J; Smith JG; Esko T; Hayward C; Gyllensten U; Landen M; Siegbahn A; Wilson JF; Wallentin L; Butterworth AS; Holmes MV; Ingelsson E; Mälarstig A

Article: SCIENTIFIC REPORTS. 2020;10(1):8233

CDH6 and HAGH protein levels in plasma associate with Alzheimer's disease in APOE ε4 carriers.

Ahmad S; Milan MDC; Hansson O; Demirkan A; Agustin R; Sáez ME; Giagtzoglou N; Cabrera-Socorro A; Bakker MHM; Ramirez A; Hankemeier T; Stomrud E; Mattsson-Carlgren N; Scheltens P; van der Flier WM; Ikram MA; Malarstig A; Teunissen CE; Amin N; van Duijn CM

Article: HEART. 2020;106(5):342-349

Identification of novel pheno-groups in heart failure with preserved ejection fraction using machine learning.

Hedman ÅK; Hage C; Sharma A; Brosnan MJ; Buckbinder L; Gan L-M; Shah SJ; Linde CM; Donal E; Daubert J-C; Mälarstig A; Ziemek D; Lund L

Article: ATHEROSCLEROSIS. 2020;295:25-30

The plasma protein profile and cardiovascular risk differ between intima-media thickness of the common carotid artery and the bulb: A meta-analysis and a longitudinal evaluation.

Lind L; Gigante B; Borne Y; Mälarstig A; Sundström J; Ärnlöv J; Ingelsson E; Baldassarre D; Tremoli E; Veglia F; Hamsten A; Orho-Melander M; Nilsson J; Melander O; Engström G

Article: NATURE COMMUNICATIONS. 2020;11(1):163

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Shah S; Henry A; Roselli C; Lin H; Sveinbjörnsson G; Fatemifar G; Hedman ÅK; Wilk JB; Morley MP; Chaffin MD; Helgadottir A; Verweij N; Dehghan A; Almgren P; Andersson C; Aragam KG; Ärnlöv J; Backman JD; Biggs ML; Bloom HL; Brandimarto J; Brown MR; Buckbinder L; Carey DJ; Chasman DI; Chen X; Chen X; Chung J; Chutkow W; Cook JP; Delgado GE; Denaxas S; Doney AS; Dörr M; Dudley SC; Dunn ME; Engström G; Esko T; Felix SB; Finan C; Ford I; Ghanbari M; Ghasemi S; Giedraitis V; Giulianini F; Gottdiener JS; Gross S; Guðbjartsson DF; Gutmann R; Haggerty CM; van der Harst P; Hyde CL; Ingelsson E; Jukema JW; Kavousi M; Khaw K-T; Kleber ME; Køber L; Koekemoer A; Langenberg C; Lind L; Lindgren CM; London B; Lotta LA; Lovering RC; Luan J; Magnusson P; Mahajan A; Margulies KB; März W; Melander O; Mordi IR; Morgan T; Morris AD; Morris AP; Morrison AC; Nagle MW; Nelson CP; Niessner A; Niiranen T; O'Donoghue ML; Owens AT; Palmer CNA; Parry HM; Perola M; Portilla-Fernandez E; Psaty BM; Regeneron Genetics Center; Rice KM; Ridker PM; Romaine SPR; Rotter JI; Salo P; Salomaa V; van Setten J; Shalaby AA; Smelser DT; Smith NL; Stender S; Stott DJ; Svensson P; Tammesoo M-L; Taylor KD; Teder-Laving M; Teumer A; Thorgeirsson G; Thorsteinsdottir U; Torp-Pedersen C; Trompet S; Tyl B; Uitterlinden AG; Veluchamy A; Völker U; Voors AA; Wang X; Wareham NJ; Waterworth D; Weeke PE; Weiss R; Wiggins KL; Xing H; Yerges-Armstrong LM; Yu B; Zannad F; Zhao JH; Hemingway H; Samani NJ; McMurray JJV; Yang J; Visscher PM; Newton-Cheh C; Malarstig A; Holm H; Lubitz SA; Sattar N; Holmes MV; Cappola TP; Asselbergs FW; Hingorani AD; Kuchenbaecker K; Ellinor PT; Lang CC; Stefansson K; Smith JG; Vasan RS; Swerdlow DI; Lumbers RT

Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2019;7(1):169

Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer's disease.

Whelan CD; Mattsson N; Nagle MW; Vijayaraghavan S; Hyde C; Janelidze S; Stomrud E; Lee J; Fitz L; Samad TA; Ramaswamy G; Margolin RA; Malarstig A; Hansson O

Article: NATURE GENETICS. 2019;51(7):1082-1091

A genetics-led approach defines the drug target landscape of 30 immune-related traits.

Fang H; ULTRA-DD Consortium; De Wolf H; Knezevic B; Burnham KL; Osgood J; Sanniti A; Lledó Lara A; Kasela S; De Cesco S; Wegner JK; Handunnetthi L; McCann FE; Chen L; Sekine T; Brennan PE; Marsden BD; Damerell D; O'Callaghan CA; Bountra C; Bowness P; Sundström Y; Milani L; Berg L; Göhlmann HW; Peeters PJ; Fairfax BP; Sundström M; Knight JC

Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38(10):2505-2518

Associations of Circulating Protein Levels With Lipid Fractions in the General Population.

Figarska SM; Gustafsson S; Sundström J; Ärnlöv J; Mälarstig A; Elmståhl S; Fall T; Lind L; Ingelsson E

Article: WELLCOME OPEN RESEARCH. 2018;3:13

Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung function.

Adewoye AB; Shrine N; Odenthal-Hesse L; Welsh S; Malarstig A; Jelinsky S; Kilty I; Tobin MD; Hollox EJ; Wain LV

Article: NATURE GENETICS. 2017;49(12):1758-1766

Exome-wide association study of plasma lipids in >300,000 individuals.

Liu DJ; Peloso GM; Yu H; Butterworth AS; Wang X; Mahajan A; Saleheen D; Emdin C; Alam D; Alves AC; Amouyel P; Di Angelantonio E; Arveiler D; Assimes TL; Auer PL; Baber U; Ballantyne CM; Bang LE; Benn M; Bis JC; Boehnke M; Boerwinkle E; Bork-Jensen J; Bottinger EP; Brandslund I; Brown M; Busonero F; Caulfield MJ; Chambers JC; Chasman DI; Chen YE; Chen Y-DI; Chowdhury R; Christensen C; Chu AY; Connell JM; Cucca F; Cupples LA; Damrauer SM; Davies G; Deary IJ; Dedoussis G; Denny JC; Dominiczak A; Dubé M-P; Ebeling T; Eiriksdottir G; Esko T; Farmaki A-E; Feitosa MF; Ferrario M; Ferrieres J; Ford I; Fornage M; Franks PW; Frayling TM; Frikke-Schmidt R; Fritsche LG; Frossard P; Fuster V; Ganesh SK; Gao W; Garcia ME; Gieger C; Giulianini F; Goodarzi MO; Grallert H; Grarup N; Groop L; Grove ML; Gudnason V; Hansen T; Harris TB; Hayward C; Hirschhorn JN; Holmen OL; Huffman J; Huo Y; Hveem K; Jabeen S; Jackson AU; Jakobsdottir J; Jarvelin M-R; Jensen GB; Jørgensen ME; Jukema JW; Justesen JM; Kamstrup PR; Kanoni S; Karpe F; Kee F; Khera AV; Klarin D; Koistinen HA; Kooner JS; Kooperberg C; Kuulasmaa K; Kuusisto J; Laakso M; Lakka T; Langenberg C; Langsted A; Launer LJ; Lauritzen T; Liewald DCM; Lin LA; Linneberg A; Loos RJF; Lu Y; Lu X; Mägi R; Malarstig A; Manichaikul A; Manning AK; Mäntyselkä P; Marouli E; Masca NGD; Maschio A; Meigs JB; Melander O; Metspalu A; Morris AP; Morrison AC; Mulas A; Müller-Nurasyid M; Munroe PB; Neville MJ; Nielsen JB; Nielsen SF; Nordestgaard BG; Ordovas JM; Mehran R; O'Donnell CJ; Orho-Melander M; Molony CM; Muntendam P; Padmanabhan S; Palmer CNA; Pasko D; Patel AP; Pedersen O; Perola M; Peters A; Pisinger C; Pistis G; Polasek O; Poulter N; Psaty BM; Rader DJ; Rasheed A; Rauramaa R; Reilly DF; Reiner AP; Renström F; Rich SS; Ridker PM; Rioux JD; Robertson NR; Roden DM; Rotter JI; Rudan I; Salomaa V; Samani NJ; Sanna S; Sattar N; Schmidt EM; Scott RA; Sever P; Sevilla RS; Shaffer CM; Sim X; Sivapalaratnam S; Small KS; Smith AV; Smith BH; Somayajula S; Southam L; Spector TD; Speliotes EK; Starr JM; Stirrups KE; Stitziel N; Strauch K; Stringham HM; Surendran P; Tada H; Tall AR; Tang H; Tardif J-C; Taylor KD; Trompet S; Tsao PS; Tuomilehto J; Tybjaerg-Hansen A; van Zuydam NR; Varbo A; Varga TV; Virtamo J; Waldenberger M; Wang N; Wareham NJ; Warren HR; Weeke PE; Weinstock J; Wessel J; Wilson JG; Wilson PWF; Xu M; Yaghootkar H; Young R; Zeggini E; Zhang H; Zheng NS; Zhang W; Zhang Y; Zhou W; Zhou Y; Zoledziewska M; Charge Diabetes Working Group; EPIC-InterAct Consortium; EPIC-CVD Consortium; GOLD Consortium; VA Million Veteran Program; Howson JMM; Danesh J; McCarthy MI; Cowan CA; Abecasis G; Deloukas P; Musunuru K; Willer CJ; Kathiresan S

Article: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):429-444

Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke.

Mahdessian H; Perisic Matic L; Lengquist M; Gertow K; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Tremoli E; Hamsten A; Eriksson P; Hedin U; Mälarstig A; IMPROVE study group

Article: PLOS GENETICS. 2017;13(4):e1006706

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.

Folkersen L; Fauman E; Sabater-Lleal M; Strawbridge RJ; Frånberg M; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Enroth S; Johansson Å; Enroth SB; Gustafsson S; Lind L; Lindgren C; Morris AP; Giedraitis V; Silveira A; Franco-Cereceda A; Tremoli E; IMPROVE study group; Gyllensten U; Ingelsson E; Brunak S; Eriksson P; Ziemek D; Hamsten A; Mälarstig A

Article: HUMAN MOLECULAR GENETICS. 2016;25(9):1867-1874

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.

Hinds DA; Buil A; Ziemek D; Martinez-Perez A; Malik R; Folkersen L; Germain M; Mälarstig A; Brown A; Soria JM; Dichgans M; Bing N; Franco-Cereceda A; Souto JC; Dermitzakis ET; Hamsten A; Worrall BB; Tung JY; METASTROKE Consortium, INVENT Consortium; Sabater-Lleal M

Article: CIRCULATION. 2016;133(13):1230-1239

Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk Factors.

Leander K; Mälarstig A; Van't Hooft FM; Hyde C; Hellénius M-L; Troutt JS; Konrad RJ; Öhrvik J; Hamsten A; de Faire U

Article: PLOS ONE. 2016;11(10):e0164041

The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro.

Miller S; Henry AP; Hodge E; Kheirallah AK; Billington CK; Rimington TL; Bhaker SK; Obeidat M; Melén E; Merid SK; Swan C; Gowland C; Nelson CP; Stewart CE; Bolton CE; Kilty I; Malarstig A; Parker SG; Moffatt MF; Wardlaw AJ; Hall IP; Sayers I

Article: JOURNAL OF INTERNAL MEDICINE. 2014;275(6):640-651

The HLA locus contains novel foetal susceptibility alleles for congenital heart block with significant paternal influence.

Meisgen S; Östberg T; Salomonsson S; Ding B; Eliasson H; Mälarstig A; Alfredsson L; Klareskog L; Hamsten A; Olsson T; Axelsson T; Swedish Congenital Heart Block Study Group; Gadler F; Jonzon A; Sonesson S-E; Kockum I; Wahren-Herlenius M

Article: PLOS ONE. 2014;9(8):e104082

Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease.

Sabater-Lleal M; Mälarstig A; Folkersen L; Soler Artigas M; Baldassarre D; Kavousi M; Almgren P; Veglia F; Brusselle G; Hofman A; Engström G; Franco OH; Melander O; Paulsson-Berne G; Watkins H; Eriksson P; Humphries SE; Tremoli E; de Faire U; Tobin MD; Hamsten A

Article: PLOS ONE. 2014;9(12):e111156

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.

Baumert J; Huang J; McKnight B; Sabater-Lleal M; Steri M; Chu AY; Trompet S; Lopez LM; Fornage M; Teumer A; Tang W; Rudnicka AR; Mälarstig A; Hottenga J-J; Kavousi M; Lahti J; Tanaka T; Hayward C; Huffman JE; Morange P-E; Rose LM; Basu S; Rumley A; Stott DJ; Buckley BM; de Craen AJM; Sanna S; Masala M; Biffar R; Homuth G; Silveira A; Sennblad B; Goel A; Watkins H; Müller-Nurasyid M; Rückerl R; Taylor K; Chen M-H; de Geus EJC; Hofman A; Witteman JCM; de Maat MPM; Palotie A; Davies G; Siscovick DS; Kolcic I; Wild SH; Song J; McArdle WL; Ford I; Sattar N; Schlessinger D; Grotevendt A; Franzosi MG; Illig T; Waldenberger M; Lumley T; Tofler GH; Willemsen G; Uitterlinden AG; Rivadeneira F; Räikkönen K; Chasman DI; Folsom AR; Lowe GD; Westendorp RGJ; Slagboom PE; Cucca F; Wallaschofski H; Strawbridge RJ; Seedorf U; Koenig W; Bis JC; Mukamal KJ; van Dongen J; Widen E; Franco OH; Starr JM; Liu K; Ferrucci L; Polasek O; Wilson JF; Oudot-Mellakh T; Campbell H; Navarro P; Bandinelli S; Eriksson J; Boomsma DI; Dehghan A; Clarke R; Hamsten A; Boerwinkle E; Jukema JW; Naitza S; Ridker PM; Völzke H; Deary IJ; Reiner AP; Trégouët D-A; O'Donnell CJ; Strachan DP; Peters A; Smith NL

Article: CIRCULATION. 2013;128(12):1310-1324

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Sabater-Lleal M; Huang J; Chasman D; Naitza S; Dehghan A; Johnson AD; Teumer A; Reiner AP; Folkersen L; Basu S; Rudnicka AR; Trompet S; Mälarstig A; Baumert J; Bis JC; Guo X; Hottenga JJ; Shin S-Y; Lopez LM; Lahti J; Tanaka T; Yanek LR; Oudot-Mellakh T; Wilson JF; Navarro P; Huffman JE; Zemunik T; Redline S; Mehra R; Pulanic D; Rudan I; Wright AF; Kolcic I; Polasek O; Wild SH; Campbell H; Curb JD; Wallace R; Liu S; Eaton CB; Becker DM; Becker LC; Bandinelli S; Räikkönen K; Widen E; Palotie A; Fornage M; Green D; Gross M; Davies G; Harris SE; Liewald DC; Starr JM; Williams FMK; Grant PJ; Spector TD; Strawbridge RJ; Silveira A; Sennblad B; Rivadeneira F; Uitterlinden AG; Franco OH; Hofman A; van Dongen J; Willemsen G; Boomsma DI; Yao J; Swords Jenny N; Haritunians T; McKnight B; Lumley T; Taylor KD; Rotter JI; Psaty BM; Peters A; Gieger C; Illig T; Grotevendt A; Homuth G; Völzke H; Kocher T; Goel A; Franzosi MG; Seedorf U; Clarke R; Steri M; Tarasov KV; Sanna S; Schlessinger D; Stott DJ; Sattar N; Buckley BM; Rumley A; Lowe GD; McArdle WL; Chen M-H; Tofler GH; Song J; Boerwinkle E; Folsom AR; Rose LM; Franco-Cereceda A; Teichert M; Ikram MA; Mosley TH; Bevan S; Dichgans M; Rothwell PM; Sudlow CLM; Hopewell JC; Chambers JC; Saleheen D; Kooner JS; Danesh J; Nelson CP; Erdmann J; Reilly MP; Kathiresan S; Schunkert H; Morange P-E; Ferrucci L; Eriksson JG; Jacobs D; Deary IJ; Soranzo N; Witteman JCM; de Geus EJC; Tracy RP; Hayward C; Koenig W; Cucca F; Jukema JW; Eriksson P; Seshadri S; Markus HS; Watkins H; Samani NJ; VTE Consortium; STROKE Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2); C4D Consortium; CARDIoGRAM Consortium; Wallaschofski H; Smith NL; Tregouet D; Ridker PM; Tang W; Strachan DP; Hamsten A; O'Donnell CJ

Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2013;98(3):668-676

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

van Meurs JBJ; Pare G; Schwartz SM; Hazra A; Tanaka T; Vermeulen SH; Cotlarciuc I; Yuan X; Mälarstig A; Bandinelli S; Bis JC; Blom H; Brown MJ; Chen C; Chen Y-D; Clarke RJ; Dehghan A; Erdmann J; Ferrucci L; Hamsten A; Hofman A; Hunter DJ; Goel A; Johnson AD; Kathiresan S; Kampman E; Kiel DP; Kiemeney LALM; Chambers JC; Kraft P; Lindemans J; McKnight B; Nelson CP; O'Donnell CJ; Psaty BM; Ridker PM; Rivadeneira F; Rose LM; Seedorf U; Siscovick DS; Schunkert H; Selhub J; Ueland PM; Vollenweider P; Waeber G; Waterworth DM; Watkins H; Witteman JCM; den Heijer M; Jacques P; Uitterlinden AG; Kooner JS; Rader DJ; Reilly MP; Mooser V; Chasman DI; Samani NJ; Ahmadi KR

Article: RESPIRATORY RESEARCH. 2013;14(1):77

HTR4 gene structure and altered expression in the developing lung.

Hodge E; Nelson CP; Miller S; Billington CK; Stewart CE; Swan C; Malarstig A; Henry AP; Gowland C; Melén E; Hall IP; Sayers I

Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2012;32(6):1526-1534

Common and low-frequency genetic variants in the PCSK9 locus influence circulating PCSK9 levels.

Chernogubova E; Strawbridge R; Mahdessian H; Mälarstig A; Krapivner S; Gigante B; Hellénius M-L; de Faire U; Franco-Cereceda A; Syvänen A-C; Troutt JS; Konrad RJ; Eriksson P; Hamsten A; van 't Hooft FM

Article: PLOS ONE. 2012;7(2):e32306

Combined chromatin and expression analysis reveals specific regulatory mechanisms within cytokine genes in the macrophage early immune response.

Iglesias MJ; Reilly S-J; Emanuelsson O; Sennblad B; Pirmoradian Najafabadi M; Folkersen L; Mälarstig A; Lagergren J; Eriksson P; Hamsten A; Odeberg J

Article: DIABETES. 2011;60(10):2624-2634

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

Strawbridge RJ; Dupuis J; Prokopenko I; Barker A; Ahlqvist E; Rybin D; Petrie JR; Travers ME; Bouatia-Naji N; Dimas AS; Nica A; Wheeler E; Chen H; Voight BF; Taneera J; Kanoni S; Peden JF; Turrini F; Gustafsson S; Zabena C; Almgren P; Barker DJP; Barnes D; Dennison EM; Eriksson JG; Eriksson P; Eury E; Folkersen L; Fox CS; Frayling TM; Goel A; Gu HF; Horikoshi M; Isomaa B; Jackson AU; Jameson KA; Kajantie E; Kerr-Conte J; Kuulasmaa T; Kuusisto J; Loos RJF; Luan J; Makrilakis K; Manning AK; Martínez-Larrad MT; Narisu N; Nastase Mannila M; Ohrvik J; Osmond C; Pascoe L; Payne F; Sayer AA; Sennblad B; Silveira A; Stancáková A; Stirrups K; Swift AJ; Syvänen A-C; Tuomi T; van 't Hooft FM; Walker M; Weedon MN; Xie W; Zethelius B; DIAGRAM Consortium; GIANT Consortium; MuTHER Consortium; CARDIoGRAM Consortium; C4D Consortium; Ongen H; Mälarstig A; Hopewell JC; Saleheen D; Chambers J; Parish S; Danesh J; Kooner J; Ostenson C-G; Lind L; Cooper CC; Serrano-Ríos M; Ferrannini E; Forsen TJ; Clarke R; Franzosi MG; Seedorf U; Watkins H; Froguel P; Johnson P; Deloukas P; Collins FS; Laakso M; Dermitzakis ET; Boehnke M; McCarthy MI; Wareham NJ; Groop L; Pattou F; Gloyn AL; Dedoussis GV; Lyssenko V; Meigs JB; Barroso I; Watanabe RM; Ingelsson E; Langenberg C; Hamsten A; Florez JC

Article: JOURNAL OF INTERNAL MEDICINE. 2011;270(3):229-236

Plasma CD93 concentration is a potential novel biomarker for coronary artery disease.

Mälarstig A; Silveira A; Wågsäter D; Öhrvik J; Bäcklund A; Samnegård A; Khademi M; Hellenius M-L; Leander K; Olsson T; Uhlén M; de Faire U; Eriksson P; Hamsten A

Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2011;19(4):479-484

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE.

Sandling JK; Garnier S; Sigurdsson S; Wang C; Nordmark G; Gunnarsson I; Svenungsson E; Padyukov L; Sturfelt G; Jönsen A; Bengtsson AA; Truedsson L; Eriksson C; Rantapää-Dahlqvist S; Mälarstig A; Strawbridge RJ; Hamsten A; Criswell LA; Graham RR; Behrens TW; Eloranta M-L; Alm G; Rönnblom L; Syvänen A-C

Article: NATURE GENETICS. 2011;43(4):339-344

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.

Coronary Artery Disease (C4D) Genetics Consortium

Article: CURRENT ATHEROSCLEROSIS REPORTS. 2010;12(3):159-166

Genetics of atherothrombosis and thrombophilia.

Mälarstig A; Hamsten A

Article: CIRCULATION. 2010;121(12):1382-1U45

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.

Smith NL; Chen M-H; Dehghan A; Strachan DP; Basu S; Soranzo N; Hayward C; Rudan I; Sabater-Lleal M; Bis JC; de Maat MPM; Rumley A; Kong X; Yang Q; Williams FMK; Vitart V; Campbell H; Mälarstig A; Wiggins KL; Van Duijn CM; McArdle WL; Pankow JS; Johnson AD; Silveira A; McKnight B; Uitterlinden AG; Wellcome Trust Case Control Consortium; ; Aleksic N; Meigs JB; Peters A; Koenig W; Cushman M; Kathiresan S; Rotter JI; Bovill EG; Hofman A; Boerwinkle E; Tofler GH; Peden JF; Psaty BM; Leebeek F; Folsom AR; Larson MG; Spector TD; Wright AF; Wilson JF; Hamsten A; Lumley T; Witteman JCM; Tang W; O'Donnell CJ

Article: NEW ENGLAND JOURNAL OF MEDICINE. 2009;361(26):2518-2528

Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

Clarke R; Peden JF; Hopewell JC; Kyriakou T; Goel A; Heath SC; Parish S; Barlera S; Franzosi MG; Rust S; Bennett D; Silveira A; Malarstig A; Green FR; Lathrop M; Gigante B; Leander K; de Faire U; Seedorf U; Hamsten A; Collins R; Watkins H; Farrall M; PROCARDIS Consortium

Article: PLOS ONE. 2009;4(11):e7677

Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.

Folkersen L; Kyriakou T; Goel A; Peden J; Mälarstig A; Paulsson-Berne G; Hamsten A; Hugh Watkins; Franco-Cereceda A; Gabrielsen A; Eriksson P; PROCARDIS consortia

Article: PLOS GENETICS. 2009;5(11):e1000730

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

Chasman DI; Paré G; Mora S; Hopewell JC; Peloso G; Clarke R; Cupples LA; Hamsten A; Kathiresan S; Mälarstig A; Ordovas JM; Ripatti S; Parker AN; Miletich JP; Ridker PM

Article: MOLECULAR MEDICINE REPORTS. 2009;2(6):971-976

Tumour-derived adhesion factor in colorectal cancer.

Mälarstig A; Wågsäter D; Löfgren S; Hugander A; Zar N; Dimberg J

Article: BLOOD. 2009;114(7):1417-1422

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.

Mälarstig A; Buil A; Souto JC; Clarke R; Blanco-Vaca F; Fontcuberta J; Peden J; Andersen M; Silveira A; Barlera S; Seedorf U; Watkins H; Almasy L; Hamsten A; Soria JM; Genetic Analysis of Idiopathic Thrombophilia (GAIT

Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2009;2(2):142-150

Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.

Paré G; Chasman DI; Parker AN; Zee RRY; Mälarstig A; Seedorf U; Collins R; Watkins H; Hamsten A; Miletich JP; Ridker PM

Article: CLINICAL SCIENCE. 2009;116(6):507-512

IGF-I/IGFBP-3 ratio: a mechanistic insight into the metabolic syndrome.

Sierra-Johnson J; Romero-Corral A; Somers VK; Lopez-Jimenez F; Mälarstig A; Brismar K; Hamsten A; Fisher RM; Hellénius M-L

Article: HEART. 2008;94(6):724-729

Raised interleukin-10 is an indicator of poor outcome and enhanced systemic inflammation in patients with acute coronary syndrome.

Mälarstig A; Eriksson P; Hamsten A; Lindahl B; Wallentin L; Siegbahn A

Article: CLINICAL CHEMISTRY. 2008;54(5):833-840

Genetic variants of tumor necrosis factor superfamily, member 4 (TNFSF4), and risk of incident atherothrombosis and venous thromboembolism.

Mälarstig A; Eriksson P; Rose L; Diehl KA; Hamsten A; Ridker PM; Zee RYL

Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2008;28(5):975-982

Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction.

Mälarstig A; Sigurdsson S; Eriksson P; Paulsson-Berne G; Hedin U; Wallentin L; Siegbahn A; Hamsten A; Syvänen A-C

Article: THROMBOSIS RESEARCH. 2007;120(3):407-413

The intersubject variability of tissue factor mRNA production in human monocytes--relation with the toll-like receptor 4.

Mälarstig A; Siegbahn A

Article: THROMBOSIS RESEARCH. 2007;119(4):467-473

Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome.

Mälarstig A; Wallentin L; Siegbahn A

Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2006;26(7):1667-1673

Soluble CD40L levels are regulated by the -3459 A>G polymorphism and predict myocardial infarction and the efficacy of antithrombotic treatment in non-ST elevation acute coronary syndrome.

Mälarstig A; Lindahl B; Wallentin L; Siegbahn A

Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(12):2667-2672

Genetic variations in the tissue factor gene are associated with clinical outcome in acute coronary syndrome and expression levels in human monocytes.

Mälarstig A; Tenno T; Johnston N; Lagerqvist B; Axelsson T; Syvänen A-C; Wallentin L; Siegbahn A

Article: THROMBOSIS RESEARCH. 2003;112(3):175-183

A quantitative real-time PCR method for tissue factor mRNA.

Mälarstig A; Tenno T; Jossan S; Aberg M; Siegbahn A

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