Ana Teixeira

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About me

Ana Teixeira was born in 1974 in Vila Verde, Portugal, and in 1997 graduated from the Technical University of Lisbon (now University of Lisbon) with a degree in Chemical Engineering. She did doctoral studies at the University of Wisconsin-Madison, USA, and her dissertation on bionanotechnology was presented in 2003.

After performing postdoc work at Karolinska Institutet in 2003-2008, Teixeira has been leading a research team at KI since 2008. In 2018 she became Docent in Nanomedicine at the Department of Medical Biochemistry and Biophysics.

Research

The Teixeira Lab uses a multi-disciplinary approach including materials science, biophysics and cell biology to understand how cells interact with their microenvironment.

Selected publications

Article: NATURE NANOTECHNOLOGY. 2024;19(2):237-245

Multivalent insulin receptor activation using insulin-DNA origami nanostructures.

Spratt J; Dias JM; Kolonelou C; Kiriako G; Engström E; Petrova E; Karampelias C; Cervenka I; Papanicolaou N; Lentini A; Reinius B; Andersson O; Ambrosetti E; Ruas JL; Teixeira AI
Article: ACS NANO. 2021;15(2):3441-3452

Spatial Regulation of T-Cell Signaling by Programmed Death-Ligand 1 on Wireframe DNA Origami Flat Sheets.

Fang T; Alvelid J; Spratt J; Ambrosetti E; Testa I; Teixeira AI
Article: NATURE NANOTECHNOLOGY. 2021;16(1):85-95

A DNA-nanoassembly-based approach to map membrane protein nanoenvironments.

Ambrosetti E; Bernardinelli G; Hoffecker I; Hartmanis L; Kiriako G; de Marco A; Sandberg R; Högberg B; Teixeira AI
Article: NUCLEIC ACIDS RESEARCH. 2020;48(10):5777-5787

Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers.

Verheyen T; Fang T; Lindenhofer D; Wang Y; Akopyan K; Lindqvist A; Högberg B; Teixeira AI
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(6):2978-2986

Modeling the transport of nuclear proteins along single skeletal muscle cells.

Taylor-Weiner H; Grigsby CL; Ferreira DMS; Dias JM; Stevens MM; Ruas JL; Teixeira AI
Article: MOLECULAR METABOLISM. 2018;7:12-22

Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation.

Mills R; Taylor-Weiner H; Correia JC; Agudelo LZ; Allodi I; Kolonelou C; Martinez-Redondo V; Ferreira DMS; Nichterwitz S; Comley LH; Lundin V; Hedlund E; Ruas JL; Teixeira AI
Article: CELL REPORTS. 2014;8(3):665-670

CtBPs sense microenvironmental oxygen levels to regulate neural stem cell state.

Dias JM; Ilkhanizadeh S; Karaca E; Duckworth JK; Lundin V; Rosenfeld MG; Ericson J; Hermanson O; Teixeira AI
Article: NATURE METHODS. 2014;11(8):841-846

Spatial control of membrane receptor function using ligand nanocalipers.

Shaw A; Lundin V; Petrova E; Fördős F; Benson E; Al-Amin A; Herland A; Blokzijl A; Högberg B; Teixeira AI

Articles

Article: JOURNAL OF MOLECULAR BIOLOGY. 2023;435(20):168262

Affinity Maturated Transferrin Receptor Apical Domain Blocks Machupo Virus Glycoprotein Binding.

Sjöström DJ; Grill B; Ambrosetti E; Veetil AA; Mohlin C; Teixeira AI; Oberdofer G; Bjelic S
Article: ACS APPLIED BIO MATERIALS. 2023;6(9):3790-3797

Live Detection of Neural Progenitors and Glioblastoma Cells by an Oligothiophene Derivative.

Ilkhanizadeh S; Gracias A; Åslund AKO; Bäck M; Simon R; Kavanagh E; Migliori B; Neofytou C; Nelander S; Westermark B; Uhrbom L; Forsberg-Nilsson K; Konradsson P; Teixeira AI; Uhlén P; Joseph B; Hermanson O; Nilsson KPR
Article: SCIENCE ADVANCES. 2022;8(41):eabm1847

Cellular shape reinforces niche to stem cell signaling in the small intestine.

Pentinmikko N; Lozano R; Scharaw S; Andersson S; Englund JI; Castillo-Azofeifa D; Gallagher A; Broberg M; Song K-Y; Sola Carvajal A; Speidel AT; Sundstrom M; Allbritton N; Stevens MM; Klein OD; Teixeira A; Katajisto P
Article: ACS APPLIED BIO MATERIALS. 2022;5(7):3310-3319

Patterned Carboxymethyl-Dextran Functionalized Surfaces Using Organic Mixed Monolayers for Biosensing Applications.

Ambrosetti E; Conti M; Teixeira AI; Zilio SD
Article: FEBS JOURNAL. 2022;289(10):2935-2947

Motif-driven protein binder design towards transferrin receptor helical domain.

Sjöström DJ; Mohlin C; Ambrosetti E; Garforth SJ; Teixeira AI; Bjelic S
Article: ADVANCED MATERIALS. 2021;33(29):e2008457

DNA Origami Penetration in Cell Spheroid Tissue Models is Enhanced by Wireframe Design.

Wang Y; Benson E; Fördős F; Lolaico M; Baars I; Fang T; Teixeira AI; Högberg B
Article: BIOTECHNOLOGY AND BIOENGINEERING. 2021;118(6):2234-2242

Effects of topological constraints on the alignment and maturation of multinucleated myotubes.

Song K-Y; Correia JC; Ruas JL; Teixeira AI
Article: SMALL. 2019;15(1):e1803628

Solution-Controlled Conformational Switching of an Anchored Wireframe DNA Nanostructure.

Hoffecker IT; Chen S; Gådin A; Bosco A; Teixeira AI; Högberg B
Article: MICROFLUIDICS AND NANOFLUIDICS. 2018;22(11):135

Enhancement of the surface free energy of PDMS for reversible and leakage-free bonding of PDMS-PS microfluidic cell-culture systems

Song K-Y; Zhang H; Zhang W-J; Teixeira A
Article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2016;55(31):8869-8872

Computer-Aided Production of Scaffolded DNA Nanostructures from Flat Sheet Meshes.

Benson E; Mohammed A; Bosco A; Teixeira AI; Orponen P; Högberg B
Article: STEM CELL REPORTS. 2014;3(3):502-515

Neural stem cell differentiation is dictated by distinct actions of nuclear receptor corepressors and histone deacetylases.

Castelo-Branco G; Lilja T; Wallenborg K; Falcão AM; Marques SC; Gracias A; Solum D; Paap R; Walfridsson J; Teixeira AI; Rosenfeld MG; Jepsen K; Hermanson O
Article: BIOMATERIALS. 2014;35(6):1907-1913

Preservation of aortic root architecture and properties using a detergent-enzymatic perfusion protocol.

Friedrich LH; Jungebluth P; Sjöqvist S; Lundin V; Haag JC; Lemon G; Gustafsson Y; Ajalloueian F; Sotnichenko A; Kielstein H; Burguillos MA; Joseph B; Teixeira AI; Lim ML; Macchiarini P
Article: BIOMATERIALS. 2014;35(5):1420-1428

A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons.

Zhang D; Pekkanen-Mattila M; Shahsavani M; Falk A; Teixeira AI; Herland A
Article: PLOS ONE. 2013;8(8):e72409

Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells.

Abdelhady S; Kitambi SS; Lundin V; Aufschnaiter R; Sekyrova P; Sinha I; Lundgren KT; Castelo-Branco G; Linnarsson S; Wedlich-Söldner R; Teixeira A; Andäng M
Article: BIOMATERIALS. 2012;33(17):4319-4326

The concept of in vivo airway tissue engineering.

Jungebluth P; Bader A; Baiguera S; Möller S; Jaus M; Lim ML; Fried K; Kjartansdóttir KR; Go T; Nave H; Harringer W; Lundin V; Teixeira AI; Macchiarini P
Article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2011;50(52):12529-12533

Electrochemical control of growth factor presentation to steer neural stem cell differentiation.

Herland A; Persson KM; Lundin V; Fahlman M; Berggren M; Jager EWH; Teixeira AI
Article: PLOS ONE. 2011;6(4):e18624

Control of neural stem cell survival by electroactive polymer substrates.

Lundin V; Herland A; Berggren M; Jager EWH; Teixeira AI
Article: MRS BULLETIN. 2010;35(8):591-596

Designing and Engineering Stem Cell Niches

Teixeira AI; Hermanson O; Werner C
Article: BIOMATERIALS. 2009;30(27):4567-4572

The promotion of neuronal maturation on soft substrates.

Teixeira AI; Ilkhanizadeh S; Wigenius JA; Duckworth JK; Inganäs O; Hermanson O
Article: CELL DEATH AND DIFFERENTIATION. 2009;16(9):1256-1265

p57Kip2 is a repressor of Mash1 activity and neuronal differentiation in neural stem cells.

Joseph B; Andersson ER; Vlachos P; Södersten E; Liu L; Teixeira AI; Hermanson O
Article: BIOMATERIALS. 2007;28(27):3936-3943

Inkjet printing of macromolecules on hydrogels to steer neural stem cell differentiation.

Ilkhanizadeh S; Teixeira AI; Hermanson O
Article: BIOMATERIALS. 2006;27(21):3945-3954

The effect of environmental factors on the response of human corneal epithelial cells to nanoscale substrate topography.

Teixeira AI; McKie GA; Foley JD; Bertics PJ; Nealey PF; Murphy CJ
Article: DEVELOPMENTAL NEUROSCIENCE. 2006;28(1-2):118-127

Recording Notch signaling in real time.

Hansson EM; Teixeira AI; Gustafsson MV; Dohda T; Chapman G; Meletis K; Muhr J; Lendahl U
Article: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A. 2004;71(3):369-376

Responses of human keratocytes to micro- and nanostructured substrates.

Teixeira AI; Nealey PF; Murphy CJ
Article: JOURNAL OF CELL SCIENCE. 2004;117(Pt 15):3153-3164

Biological length scale topography enhances cell-substratum adhesion of human corneal epithelial cells.

Karuri NW; Liliensiek S; Teixeira AI; Abrams G; Campbell S; Nealey PF; Murphy CJ
Article: JOURNAL OF CELL SCIENCE. 2003;116(Pt 10):1881-1892

Epithelial contact guidance on well-defined micro- and nanostructured substrates.

Teixeira AI; Abrams GA; Bertics PJ; Murphy CJ; Nealey PF
Article: ADVANCED MATERIALS. 2002;14(20):1468-1472

Fabrication of polymeric substrates with well-defined nanometer-scale topography and tailored surface chemistry

Kim SR; Teixeira AI; Nealey PF; Wendt AE; Abbott NL
Article: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS. 2000;52(2):261-269

Adhesion and proliferation of corneal epithelial cells on self-assembled monolayers.

Franco M; Nealey PF; Campbell S; Teixeira AI; Murphy CJ
Article: BIOCATALYSIS AND BIOTRANSFORMATION. 1998;16(2):145-162

Lipase mediated resolution of γ-branched chain fatty acid methyl esters

Heinsman NWJT; Orrenius SC; Marcelis CLM; Teixeira AD; Franssen MCR; van der Padt A; Jongejan JA; de Groot A
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All other publications

Preprint: BIORXIV. 2023

Biodistribution of DNA-origami nanostructures in live zebrafish embryos with single-cell resolution

Kolonelou C; Bräutigam L; Edwards S; Engström E; Dias JM; Spratt J; Karampelias C; Wennmalm S; Brismar H; Andersson O; Teixeira AI
Review: CELL RESEARCH. 2007;17(1):56-61

Getting the right stuff: controlling neural stem cell state and fate in vivo and in vitro with biomaterials.

Teixeira AI; Duckworth JK; Hermanson O
Published conference paper: JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B. 2003;21(2):683-687

Cell behavior on lithographically defined nanostructured substrates

Teixeira AI; Abrams GA; Murphy CJ; Nealey PF

Employments

Principal Researcher, Department of Physiology and Pharmacology, Karolinska Institutet, 2023-

Degrees and Education

Docent, Karolinska Institutet, 2018

About me

Research

Selected publications

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI