Alexander Fyrdahl

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About me

As a medical physicist specializing in cardiovascular magnetic resonance imaging, my primary research interests include real-time and motion-robust imaging, three-dimensional whole-heart imaging, and non-Cartesian trajectory design. Additionally, I am dedicated to advancing the clinical application of cutting-edge imaging techniques through the development of online reconstruction and inline analysis methods.

Upon completing my doctorate at KI, where I defended my thesis titled "Applications of the Golden-Angle in Cardiovascular MRI, " I proceeded to spend two years as a postdoctoral fellow at the University of Michigan. There, I collaborated with Associate Professor Nicole Seiberlich at the Michigan Institute for Imaging Technology and Translation (MIITT). My work focused on creating methods for real-time cardiovascular imaging at low-field (0.55T) MRI scanners and contributing to lab-wide efforts on Cardiac Magnetic Resonance Fingerprinting (MRF). I developed a method for reconstructing cMRF images directly on the scanner within a clinically viable timeframe, utilizing AI-assisted Bloch equation simulations and GPU acceleration.

Since 2022, I have returned to KI and joined the Clinical Physiology research group within the Department of Molecular Medicine and Surgery. My current work revolves around motion-robust cardiovascular imaging and parametric mapping using Cardiac MRF.

Selected publications

Article: JACC-CARDIOVASCULAR IMAGING. 2023;16(4):558-559

Pulmonary Hypertension by Catheterization Is More Accurately Detected by Cardiovascular Magnetic Resonance 4D-Flow Than Echocardiography

Ramos JG; Wieslander B; Fyrdahl A; Reiter G; Reiter U; Jin N; Skott V; Melin M; Sundblad P; Sigfridsson A; Ugander M
Book chapter: ARTIFICIAL INTELLIGENCE IN CARDIOTHORACIC IMAGING. 2022;p. 201-215

Magnetic Resonance Fingerprinting: The Role of Artificial Intelligence

Fyrdahl A; Seiberlich N; Hamilton JI
Article: JACC-CARDIOVASCULAR IMAGING. 2020;13(12):2530-2542

Comprehensive Cardiovascular Magnetic Resonance Diastolic Dysfunction Grading Shows Very Good Agreement Compared With Echocardiography.

Ramos JG; Fyrdahl A; Wieslander B; Thalén S; Reiter G; Reiter U; Jin N; Maret E; Eriksson M; Caidahl K; Sörensson P; Sigfridsson A; Ugander M
Article: MAGNETIC RESONANCE IN MEDICINE. 2020;83(4):1310-1321

Sector-wise golden-angle phase contrast with high temporal resolution for evaluation of left ventricular diastolic dysfunction.

Fyrdahl A; Ramos JG; Eriksson MJ; Caidahl K; Ugander M; Sigfridsson A

Articles

Article: EUROPEAN JOURNAL OF RADIOLOGY OPEN. 2024;12:100558

Detection of acute pulmonary embolism using native repeated magnetic resonance imaging acquisitions under free-breathing and without respiratory or cardiac gating. A diagnostic accuracy study.

Medson K; Vargas Paris R; Fyrdahl A; Wiklund P; Nyren S; Westerlund E; Lindholm P
Article: MAGNETIC RESONANCE IN MEDICINE. 2023;90(3):1041-1052

Three-dimensional sector-wise golden angle-improved k-space uniformity after electrocardiogram binning.

Fyrdahl A; Ullvin A; Ramos JG; Seiberlich N; Ugander M; Sigfridsson A
Article: EUROPEAN HEART JOURNAL - IMAGING METHODS AND PRACTICE. 2023;1(1):qyad014

Non-invasive estimation of mean pulmonary artery pressure by cardiovascular magnetic resonance in under 2 min scan time

Abdula G; Ramos JG; Marlevi D; Fyrdahl A; Engblom H; Sörensson P; Giese D; Jin N; Sigfridsson A; Ugander M
Article: ACTA RADIOLOGICA. 2023;64(4):1371-1380

Feasibility of monitoring the resolution of acute pulmonary embolism with non-contrast-enhanced magnetic resonance imaging at one day, one week, one, three, and six months.

Medson K; Westerlund E; Paris RV; Fyrdahl A; Vidovic N; Nyren S; Lindholm P
Article: MAGNETIC RESONANCE IN MEDICINE. 2023;89(2):536-549

Self-calibrated through-time spiral GRAPPA for real-time, free-breathing evaluation of left ventricular function.

Franson D; Ahad J; Liu Y; Fyrdahl A; Truesdell W; Hamilton J; Seiberlich N
Article: MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. 2021;34(1):109-118

Generalization of three-dimensional golden-angle radial acquisition to reduce eddy current artifacts in bSSFP CMR imaging.

Fyrdahl A; Holst K; Caidahl K; Ugander M; Sigfridsson A
Article: RESUSCITATION. 2020;150:113-120

The effect of levosimendan on survival and cardiac performance in an ischemic cardiac arrest model - A blinded randomized placebo-controlled study in swine.

Rysz S; Lundberg J; Nordberg P; Eriksson H; Wieslander B; Lundin M; Fyrdahl A; Pernow J; Ugander M; Djärv T; Jonsson Fagerlund M
Article: BMC MEDICAL IMAGING. 2020;20(1):28

Cardiovascular magnetic resonance 4D flow analysis has a higher diagnostic yield than Doppler echocardiography for detecting increased pulmonary artery pressure.

Ramos JG; Fyrdahl A; Wieslander B; Reiter G; Reiter U; Jin N; Maret E; Eriksson M; Caidahl K; Sörensson P; Sigfridsson A; Ugander M
Article: MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. 2019;32(3):331-341

Projection-based respiratory-resolved left ventricular volume measurements in patients using free-breathing double golden-angle 3D radial acquisition.

Holst K; Fyrdahl A; Caidahl K; Ugander M; Sigfridsson A
Article: MAGNETIC RESONANCE IN MEDICINE. 2018;80(5):1847-1856

Pulmonary artery imaging under free-breathing using golden-angle radial bSSFP MRI: a proof of concept.

Fyrdahl A; Vargas Paris R; Nyrén S; Holst K; Ugander M; Lindholm P; Sigfridsson A

All other publications

Preprint: MEDRXIV. 2024

Estimation of mean pulmonary artery pressure by cardiovascular magnetic resonance four-dimensional flow and compressed sensing

Abdula G; Bergqvist P; Castaings J; Fyrdahl A; Giese D; Jin N; Testud F; Sörensson P; Sigfridsson A; Ugander M; Marlevi D
Preprint: ARXIV. 2023

Generalized super-resolution 4D Flow MRI-using ensemble learning to extend across the cardiovascular system.

Ericsson L; Hjalmarsson A; Akbar MU; Ferdian E; Bonini M; Hardy B; Schollenberger J; Aristova M; Winter P; Burris N; Fyrdahl A; Sigfridsson A; Schnell S; Figueroa CA; Nordsletten D; Young AA; Marlevi D
Preprint: MEDRXIV. 2023

Noninvasive estimation of mean pulmonary artery pressure by CMR in under 2 minutes scan time

Abdula G; Ramos J; Marlevi D; Fyrdahl A; Engblom H; Sörensson P; Giese D; Jin N; Sigfridsson A; Ugander M
Published conference paper: LECTURE NOTES IN COMPUTER SCIENCE. 2023;13958:425-434

Vortex Duration Time to Infer Pulmonary Hypertension: In-Silico Emulation and Dependence on Quantification Technique

Sabry M; Lamata P; Sigfridsson A; Keramati H; Fyrdahl A; Ugander M; Yacoub MH; Marlevi D; De Vecchi A
Editorial comment: JOURNAL OF MAGNETIC RESONANCE IMAGING. 2022;56(2):474-475

Editorial for "Aortic Pulse Wave Velocity Evaluated by 4D Flow MRI Across the Adult Lifespan".

Fyrdahl A
Meeting abstract: PROCEEDINGS OF THE INTERNATIONAL SOCIETY FOR MAGNETIC RESONANCE IN MEDICINE ... SCIENTIFIC MEETING AND EXHIBITION.. 2022

Self-calibrated through-time spiral GRAPPA for real-time, free-breathing evaluation of left ventricular function

Franson D; Ahad J; Liu Y; Fyrdahl A; Seiberlich N
Meeting abstract: PROCEEDINGS OF THE INTERNATIONAL SOCIETY FOR MAGNETIC RESONANCE IN MEDICINE ... SCIENTIFIC MEETING AND EXHIBITION.. 2022

Real-time Cardiac MRI at 0.55T using through-time spiral GRAPPA

Fyrdahl A; Seiberlich N
Meeting abstract: PROCEEDINGS OF THE INTERNATIONAL SOCIETY FOR MAGNETIC RESONANCE IN MEDICINE ... SCIENTIFIC MEETING AND EXHIBITION.. 2022

Online FIRE Reconstruction of Cardiac MRF T1, T2 and ECV maps with Neural Network Dictionary Generation and Low-Rank Subspace Reconstruction

Fyrdahl A; Seiberlich N; Hamilton J
Review: MAGNETIC RESONANCE IN MEDICINE. 2021;85(4):1821-1839

CG-SENSE revisited: Results from the first ISMRM reproducibility challenge.

Maier O; Baete SH; Fyrdahl A; Hammernik K; Harrevelt S; Kasper L; Karakuzu A; Loecher M; Patzig F; Tian Y; Wang K; Gallichan D; Uecker M; Knoll F
Preprint: ARXIV. 2020

CG-SENSE revisited: Results from the first ISMRM reproducibility challenge

Maier O; Baete SH; Fyrdahl A; Hammernik K; Harrevelt S; Kasper L; Karakuzu A; Loecher M; Patzig F; Tian Y; Wang K; Gallichan D; Uecker M; Knoll F
Thesis / dissertation: 2020

Applications of the golden angle in cardiovascular MRI

Fyrdahl, Alexander
Preprint: RESEARCH SQUARE. 2019

Cardiovascular magnetic resonance 4D flow analysis has a higher diagnostic yield than Doppler echocardiography for detecting increased pulmonary artery pressure

Ramos JG; Fyrdahl A; Wieslander B; Reiter G; Reiter U; Jin N; Maret E; Eriksson M; Caidahl K; Sörensson P; Sigfridsson A; Ugander M
Meeting abstract: EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING. 2019;20:239-240

Diastolic dysfunction grading with a comprehensive CMR protocol - feasibility and agreement compared to echocardiography

Ramos J; Fyrdahl A; Wieslander B; Thalén S; Reiter G; Reiter U; Jin N; Maret E; Eriksson M; Caidahl K; Sörensson P; Sigfridsson A; Ugander M

Grants

A Framework for Multi-dimensional Adaptive Cardiac MRI using online motion estimators

Karolinska Institutet

1 January 2024 - 31 December 2028
A Framework for Multi-dimensional Adaptive Cardiac MRI using online motion estimators

Swedish Research Council

1 January 2023 - 31 December 2026

Employments

Research Infrastructure Specialist, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023-
Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2020
Degree of Master, Medical Radiation Physics, Compressed Sensing for Time-Resolved Golden-Angle Radial Cardiac Magnetic Resonance Imaging, Department of Physics, Stockholm University, 2016

Journal reviewing

Magnetic Resonance in Medicine, Wiley, Anonymous peer review, 2021
Journal of Magnetic Resonance in Medicine, Wiley, Anonymous peer review, 2020

About me

Selected publications

Articles

All other publications

Grants

Employments

Degrees and Education

Journal reviewing

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