Improving Health Experiences - Hexi
Improving Health Experiences - Hexi
Research Group Leader
The possible relationship between symptoms and gene expression profiling is yet unknown, however several ongoing clinical trials raises the issue of the question concerning the value of studying symptom clusters to further the refinement of prognosis and the improvement of therapeutic strategies for women with early stage breast cancer. The focus of this project is symptom experience and severity in the context of chemotherapy and/or endocrine therapy treatment and linked to gene expression profiling. The main aim of this project is to study symptom clusters of patients with stage I-IIIA breast cancer undergoing 2 different standard chemotherapy treatments and endocrine treatment. The exploration of validated symptom clusters will aid assessment, management, and prioritization of care for the patient group. This study will result in: A systematic assessment of gene profile and symptoms of patients with breast cancer. A platform for evidence based development of nursing interventions for symptom relief during chemotherapy and endocrine treatment for women with breast cancer.
This study on women with breast cancer during and after chemo- and hormonal therapy compares the effect of different physical training programs in on physical and mental well-being and systemic inflammation mechanisms in blood. In a sub-group of participants, mitochondrial biogenesis and function and other molecular processes in skeletal muscle biopsies are studied. In another sub-group, the side-effect profile of the anti-hormonal treatment is investigated. The women will be randomly allocated into three arms, a control arm with usual care and two different training arms. All participants will respond to different questionnaires and have blood samples taken. In a sub-set of the participants muscle biopsies will be obtained. Some women will also be asked to participate in an interview about the experiences of training during treatment. This study will contribute to increased knowledge about the type, intensity and frequency of training that patients with breast cancer benefit most from with regards to impact on physical and mental wellbeing. Bbut above all, increase the possibility for evidence-based rehabilitation of women with breast cancer during and after active treatment.
SCREESCO – Participation in a national screening program for colorectal cancer
The purpose with screening for colorectal cancer is early diagnosis in order to achieve cure. This project is a randomized clinical trial aiming to study participation in a national screening program for colorectal cancer. Mixed methods are used to elucidate how people reason and what motivates participation and non-participation in screening for colorectal cancer. Data collection is national and includes participants from the 6 regional cancer centres. Focus group discussion for participants included in F-Hb, Coloscopy and sigmoideoscopy as well as individuals not participating are planned. A quantitative survey will follow to understand the decision process and levels of knowledge or risk and colorectal cancer in the population. Worry and health literacy will also be studied.
Lecturer Skövde Högskola
Lecturer Sophiahemmet Högskola
Lecturer Örebro University
Post doc Kate-Bolam
Delivering and participating in a psycho-educational intervention for family caregivers during palliative home care: a qualitative study from the perspectives of health professionals and family caregivers.