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Video about study in Science on stem cell scarring
Study in Science - animation by Mattias Karlén
The animation shows a simplified view of lesion development after spinal cord injuries in mice, with and without the resident neural stem cell injury response. The neural stem cells (green) respond to injury by producing progeny that migrate to the lesion site where they contribute to the forming glial scar. Without the neural stem cell response, the injury gradually expands and more nerve fibres are cut off, suggesting that the neural stem cell-derived scar tissue prevents the lesion from expanding. The findings are published by Professor Jonas Frisén and colleagues in Science 1 November 2013.