Iceland’s president visits Karolinska Institutet
State visit. Icelandic President Guðni Thorlacius Jóhannesson and his wife Eliza Reid visited Karolinska Institutet on 18 January together with the Swedish King and Queen. KI and Iceland have enjoyed many years of collaboration, both in research and student exchanges.
“Start cells” in the midbrain control whether we walk or run
Study. In research on mice, KI and the University of Copenhagen scientists, have discovered that specific start cells in various locations in the brainstem control whether the mouse walks or runs. This research may lead to new treatments for diseases and injuries that adversely affect locomotion.
New way to target growth of breast cancer cells
Study. An international team of researchers led from Karolinska Institutet and Science for Life Laboratory have found a new way of halting the growth of breast cancer cells. Hopefully their discoveries can be further developed into a new way of treating breast cancer, and possibly other types of cancer.
Oxysterols guide gut immune cells and are involved in inflammatory bowel disease
Study. Researchers at KI report that cholesterol metabolites cause specific immune cells in the large intestine to move, which lies behind the formation of the immune system's important lymphoid tissue in the intestine. The study paves the way for a new possible treatment for patients with inflammatory bowel disease.
Research groups’ move to Bioclinicum delayed
According to the previous plan, research groups from Karolinska Institutet and Karolinska University Hospital were due to move into the new Bioclinicum research building on the hospital site in Solna in mid-January 2018. However, a decision has been made to postpone the move due to IT problems.
Genetic analysis can improve depression therapy
Study. The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients. Variations within the gene that encodes the CYP2C19 enzyme results in extreme differences in the levels of escitalopram achieved in patients, according to a new study.
Proteomics analyses could present new opportunities to diagnose and treat dementias
Study. The ability to lear and memorize severely decline in the case of dementia. A new study, led by KI, suggests that particular proteins important in the communication between neurons could be targets for early interventions in patients with different types of dementias.
High impact publications
Recent publications in high impact journals where researchers from KI are main authors.
An interactive framework for whole-brain maps at cellular resolution
Fürth D, Vaissière T, Tzortzi O, Xuan Y, Märtin A, Lazaridis I, Spigolon G, Fisone G, Tomer R, Deisseroth K, Carlén M, Miller CA, Rumbaugh G, Meletis K, Nature Neuroscience (2017) Online 4 December. Technical Report.
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression
Palazon A, Tyrakis PA, Macias D, Velica P, Rundqvist H, Fitzpatrick S, Vojnovic N, Phan AT, Loman N, Hedenfalk I, Hatschek T, Lövrot J, Foukakis T, Goldrath AW, Bergh J, Johnson RS, Cancer Cell (2017) Online 13 November. Article.
Prevalence of cerebral palsy in Uganda: a population-based study
Kakooza-Mwesige A, Andrews C, Peterson S, Wabwire Mangen F, Eliasson AC, Forssberg H, Lancet Global Health (2017) Online 25 October. Article.
KI in the media
The story about KAW's support to KI
Historical. In its pursuit of excellence and pursuing long-term goals, the Knut and Alice Wallenberg Foundation has awarded billions of Swedish kroner to researchers at Karolinska Institutet over the years. The Foundation, this year celebrating its 100th anniversary, has grown into one of Europe’s largest private financiers of research.
Meet Emily Holmes
Emily Holmes is professor and principal investigator at the Department of Clinical Neuroscience at Karolinska Institutet and studies how our internal mental images are connected to our psyche.
Hear her talk about herself and her research in a video that was produced for the professors installation ceremony in the fall of 2017. More videos in our YouTube channel