Childhood sleep apnoea is common but hard to diagnose
Study. The cessation of breathing during sleep caused by enlarged tonsils is common in preschoolers and can cause serious complications, but the methods used to diagnose the condition are subjective and unreliable. The finding is reported in a thesis from Karolinska Institutet.
KI research behind the new documentary series on suicide
Broadcast. Swedish Television’s documentary series “30 liv i veckan” [30 lives a week] will begin in April. The series’ title refers to the fact that some 1,500 people committed suicide in Sweden in 2015. This is roughly equivalent to 30 lives a week, or one suicide every six hours. Researchers from Karolinska Institutet have contributed.
High impact publications
Recent publications in high impact journals where researchers from Karolinska Institutet are main authors.
Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson’s disease model
Rivetti di Val Cervo P, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng Y-H, Padrell Sánchez S, Linnarsson S, Wernig M, Harkany T, Fisone G, Arenas E, Nature Biotechnology (2017) Online 10 April. Article.
Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States
Collier AJ, Panula SP, Schell JP, Chovanec P, Plaza Reyes A, Petropoulos S, Corcoran AE, Walker R, Douagi I, Lanner F, Rugg-Gunn PJ, Cell Stem Cell (2017) Online 23 March. Article.
Association Between Rheumatoid Arthritis and Risk of Ischemic and Nonischemic Heart Failure
Mantel Ä, Holmqvist M, Andersson DC, Lund LH, Askling J, JACC (2017) Online 14 March. Article.
KI in the media
Improving anaesthesia care for children
Per-Arne Lönnqvist’s research aims to improve anaesthesia care for children. He has helped to develop the use of ultrasound for improving the precision of local anaesthetic administration and has been a pioneer in the use of alpha-2 agonists in paediatric anaesthesia and intensive care.
Reducing risk during pregnancy and childbirth
Anna-Karin Wikström researches pregnancy-related complications, especially preeclampsia. Two important lines of her research involve registry studies of risk factors during pregnancy and childbirth, and MRI studies of the placenta and the maternal brain during preeclampsia.