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Comment on current media in the matter of suspected scientific misconduct

4 May 2016. Wednesday 4 May, the former KI researcher and surgeon Paolo Macchiarini is interviewed in The Swedish Medical Association news magazine Läkartidningen and Swedish Television. In the interview in Läkartidningen, Paolo Macchiarini expresses that KI's decision to discharge him was ill-founded and further claims that KI's actions were media-driven. KI does not share this view.


 

New board proposed for KI

4 April 2016. The government has now received proposals for the members of the KI University Board (konsistoriet) whom it is to appoint. The proposals were submitted by the nomination committee, comprising County Governor Christ Heister, former University Chancellor Lars Haikola and a student representative.


 

Karolinska Institutet dismisses Macchiarini

23 April 2016. The Staff Disciplinary Board at KI has today decided to relieve Paolo Macchiarini of his duties as a researcher at KI. He is to be informed immediately that his contract has been rescinded.


 

Role of the Ethics Council to be reviewed

5 March 2016. Recent events have accentuated that there is a need to clarify and revitalise work with research ethics at KI.

More reading on Acting Vice-Chancellor Karin Dahlman-Wright's blog 


 

Government requests renewal of KI board

3 March 2016. The government has announced its decision today, 3 March, to task a nomination committee with submitting proposals for new members of the Karolinska Institutet University Board.


 

The Professors' Collegium: “We should have an atmosphere guided by ethics”

28 February 2016. On Monday 22 February, KI's Professors' Colegium met to discuss how the Collegium can contribute to restoring trust in KI. Interview with Professor Nancy Pedersen, one of the arrangers of this meeting. 


 

VC’s advisor resigns from post

23 February 2016. Professor Jan Carlstedt-Duke resigned as advisor to the vice-chancellor last Monday in order to take up other duties at the university.

Comment by Acting Vice-Chancellor Karin Dahlman-Wright.


 

Dean of Research to step down

23 February 2016. Dean Hans-Gustaf Ljunggren has requested to step down from his position as Dean of Research. Acting Vice-Chancellor Karin Dahlman-Wright comments on his decision.


 

The Macchiarini case: The story so far

23 February 2016. Misrecruitment, scientific fraud and failing implants that should never have been implanted in patients – serious allegations have been levelled for a long time against Paolo Macchiarini and KI’s conduct in connection with his activities. Following SVT’s documentary series Experimenten the flood of criticism has resulted in a crisis of confidence in the university, the resignation of the vice-chancellor and new investigations into the mistakes that have been made. Here is a brief history of the case so far.


 

Investigations and other measures related to the Macchiarini case

23 February 2016. Following the relevations concerning the researcher and surgeon Paolo Macchiarini's actions, a number of investigations and other measures have been initiated at Karolinska Institutet, as well as at the Karolinska University Hospital and other public authorities. 


 

Karin Dahlman-Wright named Acting Vice-Chancellor at Karolinska Institutet

On 18 February, the government decided to appoint Karin Dahlman-Wright as Acting Vice-Chancellor at Karolinska Institutet. Karin Dahlman-Wright was appointed Pro-Vice-Chancellor on 1 January 2016 and has been Professor of Molecular Endocrinology since 2009.

More about Karin Dahlman-Wright

University Board decision on recruitment of new vice-chancellor

At a meeting on 17 February, the the KI University Board decided to issue a request to the government regarding the promotion of Karin Dahlman-Wright as the stand-in vice-chancellor for Karolinska Institutet following the resignation of Anders Hamsten. The University Board also decided to start the recruitment process for a new ordinary vice-chancellor. At the meeting Karin Dahlman-Wright also announced that the misconduct case against surgeon Paolo Macchiarini will be re-opened and passed to the Central Ethical Review Board for comment.


 

Anders Hamsten steps down as Vice-Chancellor of Karolinska Institutet

Investigation into scientific misconduct re-opens. Professor Anders Hamsten steps down from his assignment as Vice-Chancellor of Karolinska Institutet. He declares his resignation in a debate article in the daily newspaper Dagens Nyheter. At the same time Karolinska Instutet’s investigation into scientific misconduct by Paolo Macchiarini will be re-opened.

DN Debatt on 13 February 2016: ”I am resigning my position as Vice-Chancellor of Karolinska Institutet”


 

Karolinska Institutet faces storm of criticism following documentary series on Paolo Macchiarini

KI researcher and surgeon Paolo Macchiarini’s exoneration from scientific misconduct charges, and the SVT documentary series, “Experimenten” ("The Experiments"), have together unleashed a storm of criticism against Karolinska Institutet. At an extraordinary meeting held on 4 February, Karolinska Institutet’s highest decision-making body, the University Board (Konsistoriet), decided to launch an external investigation of the Macchiarini case.

University Board launches external inquiry

4 February 2016. The external inquiry will look into events that have taken place at Karolinska Institutet from the time surgeon Paolo Macchiarini was recruited as visiting professor in 2010 to the present.

Investigators appointed in Macchiarini case

9 February 2016. The external investigator is former president and justice of the Supreme Administrative Court of Sweden, Sten Heckscher, who will be assisted by author Ingrid Carlberg and professor of biochemistry at Helsinki University, Carl Gahmberg.

Vice-Chancellor comments on board’s decision

4 Febraury 2016. The University Board also announced on 4 February that it retains full confidence in Vice-Chancellor Anders Hamsten, and that he should remain in office for the duration of the investigation.


 

Decision on Paolo Macchiarini’s employment at KI

4 February 2016. Paolo Macchiarini’s temporary contract with Karolinska Institutet, which expires on 30 November 2016, will not be extended. In the interim, his research at Karolinska Institutet will be phased out and his research group dismantled. The announcement was made on 4 February following a decision by Vice-Chancellor Anders Hamsten.

KI found inaccuracies in CV

Report: Paolo Macchiarini supplied false details in the CV he submitted ahead of his recruitment as visiting professor at KI. This is the conclusion drawn by Karolinska Institutet after looking into claims made in an article published by the US magazine Vanity Fair that Macchiarini had been untruthful in his CV.

Comments on the revelations in Vanity Fair

8 January 2016. When the Vanity Fair article was published on 5 January, Karolinska Institutet responded that it would investigate the claims “expeditiously”.


 

Comments on SVT’s documentary series “Experimenten”

28 January 2016. In its documentary series “Experimenten”, Swedish Television (SVT) investigated Karolinska Institutet Visiting Professor Paolo Macchiarini. In commenting on the documentaries, Vice-Chancellor Anders Hamsten stated that details had emerged that were unknown to Karolinska Institutet’s management and that the inquiry into allegations of scientific misconduct levelled against Paolo Macchiarini could be reopened.

Clarification of responsibilities in connection with transplantations of synthetic trachea in Sweden and Russia

29 January 2016. Following the SVT documentary series, Karolinska Institutet published a statement clarifying the respective responsibilities of the university and the university hospital regarding the activities of the investigated researcher, Paolo Macchiarini.


 

Visiting professor at Karolinska Institutet acquitted of scientific misconduct charges

28 August 2015. On 28 August 2015, Karolinska Institutet acquitted visiting professor and surgeon Paolo Macchiarini from suspicions of scientific misconduct. The complaints against Paolo Macchiarini had been lodged in June, August and September 2014 by four doctors employed at Karolinska University Hospital. The main thrust of their criticism was that seven scientific papers for which Paolo Macchiarini had primary responsibility contained inaccurate accounts of Macchiarini’s research results, and thus erroneous conclusions. Following a year’s investigation, external investigator Bengt Gerdin issued his statement that Paolo Macchiarini is guilty of scientific misconduct. However, Karolinska Institutet arrived at a different conclusion, and stated that he is merely guilty of carelessness.

Vice-Chancellor Anders Hamsten comments on the investigation into suspected scientific misconduct

28 August 2015. Following the decision to acquit Paolo Macchiarini from accusations of scientific misconduct, Vice-Chancellor Anders Hamsten stated that the main issues raised and criticised by both the complainants and Bengt Gerdin, upon which the suspicions of scientific misconduct were based, have been satisfactorily refuted by Paolo Macchiarini and his co-authors.

Information on complaints and investigations concerning previous tracheal surgery

28 August 2015. While the investigation into the allegations of scientific misconduct is underway, Karolinska Institutet announced that more inquiries are being conducted in response to other complaints against Paolo Macchiarini’s tracheal operations. Some concern suspicions of scientific misconduct, which Karolinska Institutet’s vice-chancellor is required by law to investigate; others are connected with the operations performed at Karolinska University Hospital, which are under investigation by several bodies, including the Health and Social Care Inspectorate (IVO).

Information concerning inquiry into alleged scientific misconduct

26 June 2015. On 26 June 2015, Karolinska Institutet announced that it had received 31 statements of opinion, making up some 1,000 pages of text, that along with the statement issued by external investigator Bengt Gerdin, will form part of the documentation to be examined in the case of alleged scientific misconduct concerning Paolo Macchiarini.

Comments on the Swedish Research Council’s decision to withdraw its grant to researcher suspected of misconduct

22 June 2015. While Karolinska Institutet’s investigation into the complaints of scientific misconduct has yet to be concluded, the Swedish Research Council announced that it is stopping its grants to ACTREM, a research centre for regenerative medicine at Karolinska Institutet. Karolinska Institutet commented on its decision.


 

Acquittal in misconduct case

14 April 2015. In April, the vice-chancellor of Karolinska Institutet announced his decision on another case concerning allegations of scientific misconduct against Paolo Macchiarini. The vice-chancellor acquitted Paolo Macchiarini of the charges against him.