Lectures and seminars

MBB Lunch Seminar - Mark Dawson: "Cancer Epigenetics - from mechanism to therapy"

2013-06-1412:00 to 13:00 Large seminar room (in A3:3), Scheele laboratory, Scheeles väg 2.

Mark A Dawson, Cambridge Institute for Medical Research and Wellcome Trust / CRUK Gurdon Institute, Univ Cambridge: Cancer Epigenetics - from mechanism to therapy.

Selected publications:

Cancer epigenetics: from mechanism to therapy

Dawson MA, Kouzarides T.

Cell. 2012 Jul 6;150(1):12-27

Targeting epigenetic readers in cancer.

Dawson MA, Kouzarides T, Huntly BJ.

N Engl J Med. 2012 Aug 16;367(7):647-57.

Three distinct patterns of histone H3Y41 phosphorylation mark active genes.

Dawson MA, Foster SD, Bannister AJ, Robson SC, Hannah R, Wang X, Xhemalce B, Wood AD, Green AR, Göttgens B, Kouzarides T

Cell Rep. 2012 Sep 27;2(3):470-7

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.

Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, Chan WI, Robson SC, Chung CW, Hopf C, Savitski MM, Huthmacher C, Gudgin E, Lugo D, Beinke S, Chapman TD, Roberts EJ, Soden PE, Auger KR, Mirguet O, Doehner K, Delwel R, Burnett AK, Jeffrey P, Drewes G, Lee K, Huntly BJ, Kouzarides T.

Nature. 2011 Oct 2;478(7370):529-33.

JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.

Dawson MA, Bannister AJ, Göttgens B, Foster SD, Bartke T, Green AR, Kouzarides T.

Nature. 2009 Oct 8;461(7265):819-22.

For more information please contact: Goncalo.Castelo-Branco@ki.se