KEP: Reproductive Epidemiology

“The time we spend in utero is undoubtedly the most important developmental time period of our lives; we go from one cell to a viable individual in roughly 38 weeks!”

        Sara Öberg, PhD thesis, Karolinska Institutet, 2011 

Our aims are to understand the etiology and factors influencing:

  • risks of maternal and fetal/infant health during pregnancy, delivery and after delivery;
  • associations between pregnancy and the long term prognosis for the mother and child.

For this purpose, we use population-based research registries and local data bases. The research is performed in collaboration with other research groups within the Clinical Epidemiology Unit (KEP), other research groups within Karolinska Institutet and other universities in Sweden and internationally.

Group Members

Maria Altman, MD, PhD

Sven Cnattingius, MD, PhD (group leader)

Anna-Karin Edstedt Bonamy, MD, PhD

Charlotte Elvander, Graduate student

Anna Gunnerbeck, Graduate student

Anders Hjern, MD, PhD

Stefan Johansson, MD, PhD

Krisztina Laszlo, PhD

Anna Lindam, PhD

Siavash Maghsoudlou, Graduate student

Katarina Remaeus, Graduate student

Anna Sandström, Graduate student

Olof Stephansson, MD, PhD

Anna-Karin Wikström, MD, PhD

Can Liu

Charlotte Lindblad Wollman

Fatine Khammari Nyström

Gunnar Petersson

Marija Simic

Stefan Johansson

Martina Persson

Mia Ahlberg

Nathalie Roos

Olof Stephansson

Study Summaries

Maternal overweight and obesity and risk of preterm delivery

Using the Swedish Medical Birth Register, we found that risk of preterm delivery increased with maternal BMI. Maternal overweight increased risks of both spontaneous and medically indicated extremely (<22-27 weeks) preterm delivery, while associations with very and moderately preterm delivery (28-31 and 32-36 weks, respectively) were mainly confined to medically indicated preterm delivery.

Publication: Maternal obesity and risk of preterm delivery.
Cnattingius S, Villamor E, Johansson S, Edstedt Bonamy A, Persson M, Wikström A, et al
JAMA 2013 Jun;309(22):2362-70



Our research is funded through several public funding bodies, including The Swedish Research Council (VR), The Swedish Research Council for Health, Working Life and Welfare (FORTE), Stockholm County Council (ALF), Swedish Society of Medicine, the European Unions 7th Frame Work Programme.