Publications ICMC

Here are some recent publications from ICMC.

A role for membrane shape and information processing in cardiac physiology.
Knöll R
Pflugers Arch. 2015 Jan;467(1):167-73

Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans.
Bonde Y, Breuer O, Lütjohann D, Sjöberg S, Angelin B, Rudling M
J. Lipid Res. 2014 Nov;55(11):2408-15

Influence of physiological changes in endogenous estrogen on circulating PCSK9 and LDL cholesterol.
Ghosh M, Gälman C, Rudling M, Angelin B
J. Lipid Res. 2015 Feb;56(2):463-9

Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction.
Unsöld B, Kaul A, Sbroggiò M, Schubert C, Regitz-Zagrosek V, Brancaccio M, et al
Cardiovasc. Res. 2014 Jan;101(1):97-107

Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.
Tarone G, Balligand J, Bauersachs J, Clerk A, De Windt L, Heymans S, et al
Eur. J. Heart Fail. 2014 May;16(5):494-508

A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes.
Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, et al
JCI Insight 2016 Jun;1(9):

Molecular disturbance underlies to arrhythmogenic cardiomyopathy induced by transgene content, age and exercise in a truncated PKP2 mouse model.
Moncayo-Arlandi J, Guasch E, Sanz-de la Garza M, Casado M, Garcia N, Mont L, et al
Hum. Mol. Genet. 2016 Sep;25(17):3676-3688

Changes in DNA Methylation in Mouse Lungs after a Single Intra-Tracheal Administration of Nanomaterials.
Tabish A, Poels K, Byun H, Luyts K, Baccarelli A, Martens J, et al
PLoS ONE 2017 ;12(1):e0169886

Analysis of the brain mural cell transcriptome.
He L, Vanlandewijck M, Raschperger E, Andaloussi Mäe M, Jung B, Lebouvier T, et al
Sci Rep 2016 Oct;6():35108

The mechanism of activation of skeletal muscle phosphorylase A by glycogen.
Metzger B, Helmireich E, Glaser L
Proc. Natl. Acad. Sci. U.S.A. 1967 Apr;57(4):994-1001

Canadian medical student selection and some characteristics of applicants, 1970-71.
Collishaw N, Grainger R
J Med Educ 1972 Apr;47(4):254-62

Molecular disturbance underlies to arrhythmogenic cardiomyopathy induced by transgene content, age and exercise in a truncated PKP2 mouse model.
Moncayo-Arlandi J, Guasch E, Sanz-de la Garza M, Casado M, Garcia N, Mont L, et al
Hum. Mol. Genet. 2016 Sep;25(17):3676-3688

A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes.
Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, et al
JCI Insight 2016 Jun;1(9):

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification.
Vanlandewijck M, Lebouvier T, Andaloussi Mäe M, Nahar K, Hornemann S, Kenkel D, et al
PLoS ONE 2015 ;10(11):e0143407

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Segerstolpe , Palasantza A, Eliasson P, Andersson E, Andréasson A, Sun X, et al
Cell Metab. 2016 Oct;24(4):593-607

Peptide- and Amine-Modified Glucan Particles for the Delivery of Therapeutic siRNA.
Cohen J, Shen Y, Aouadi M, Vangala P, Tencerova M, Amano S, et al
Mol. Pharm. 2016 Mar;13(3):964-978

Liver innate immune cells and insulin resistance: the multiple facets of Kupffer cells.
Jager J, Aparicio-Vergara M, Aouadi M
J. Intern. Med. 2016 Aug;280(2):209-20.

Circulating Hepcidin-25 Is Reduced by Endogenous Estrogen in Humans.
Lehtihet M, Bonde Y, Beckman L, Berinder K, Hoybye C, Rudling M, et al
PLoS ONE 2016 ;11(2):e0148802.

Desmin, desminopathy and the complexity of genetics.
Azzimato V, Gennebäck N, Tabish A, Buyandelger B, Knöll R
J. Mol. Cell. Cardiol. 2016 Mar;92():93-5
.

Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis.
Roth Flach R, Skoura A, Matevossian A, Danai L, Zheng W, Cortes C, et al
Nat Commun 2015 Dec;6():8995.

Arginase inhibition improves endothelial function in patients with familial hypercholesterolaemia irrespective of their cholesterol levels.
Kovamees O, Shemyakin A, Eriksson M, Angelin B, Pernow J
J. Intern. Med. 2016 May;279(5):477-84.

Ylva Bonde, Bo Angelin, and Mats Rudling
"Letter to the Editor: Potential Role for FGF21 as a Mediator of Thyroid Hormone Effects on Metabolic Regulation." The Journal of Clinical Endocrinology & Metabolism, 100(12), pp. L130–L131

Who is the Treatment-Seeking Young Adult with Severe Obesity: A Comprehensive Characterization with Emphasis on Mental Health.
Dreber H, Reynisdottir S, Angelin B, Hemmingsson E
PLoS ONE 2015 ;10(12):e0145273.

Activated Kupffer cells inhibit insulin sensitivity in obese mice
Michaela Tencerova*,1,2, Myriam Aouadi*,2,3,4, Pranitha Vangala*,Sarah M. Nicoloro*, Joseph C. Yawe*, Jessica L. Cohen*, Yuefei Shen*,Lorena Garcia-Menendez*,5, David J. Pedersen*, Karen Gallagher-Dorval†,Richard A. Perugini†, Olga T. Gupta‡,6 and Michael P. Czech*,4
FASEB J fj.15-270496; published ahead of print March 24, 2015,doi:10.1096/fj.15-270496

Correction: Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin.
Perisic L, Rodriguez P, Hultenby K, Sun Y, Lal M, Betsholtz C, et al
PLoS ONE 2015 ;10(5):e0126079

Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion.
Apro J, Beckman L, Angelin B, Rudling M
Biochem. Biophys. Res. Commun. 2015 Jun;461(4):592-7

Levels of atherogenic lipoproteins are unexpectedly reduced in interstitial fluid from type 2 diabetes patients.
Apro J, Parini P, Broijersén A, Angelin B, Rudling M
J. Lipid Res. 2015 Aug;56(8):1633-9

Levels of atherogenic lipoproteins are unexpectedly reduced in interstitial fluid from type 2 diabetes patients.
Apro J, Parini P, Broijersén A, Angelin B, Rudling M
J. Lipid Res. 2015 Aug;56(8):1633-9

ZBTB17 (MIZ1) Is Important for the Cardiac Stress Response and a Novel Candidate Gene for Cardiomyopathy and Heart Failure.
Buyandelger B, Mansfield C, Kostin S, Choi O, Roberts A, Ware J, et al
Circ Cardiovasc Genet 2015 Oct;8(5):643-52

Toll-Like Receptor 3 Influences Glucose Homeostasis and β-Cell Insulin Secretion.
Strodthoff D, Ma Z, Wirström T, Strawbridge R, Ketelhuth D, Engel D, et al
Diabetes 2015 Oct;64(10):3425-38

The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.
Heimbucher T, Liu Z, Bossard C, McCloskey R, Carrano A, Riedel C, et al
Cell Metab. 2015 Jul;22(1):151-63

Dendrin ablation prolongs life span by delaying kidney failure.
Weins A, Wong J, Basgen J, Gupta R, Daehn I, Casagrande L, et al
Am. J. Pathol. 2015 Aug;185(8):2143-57

Influence of physiological changes in endogenous estrogen on circulating PCSK9 and LDL cholesterol.
Ghosh M, Gälman C, Rudling M, Angelin B
J. Lipid Res. 2015 Feb;56(2):463-9

Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans.
Bonde Y, Breuer O, Lütjohann D, Sjöberg S, Angelin B, Rudling M
J. Lipid Res. 2014 Nov;55(11):2408-15

A role for membrane shape and information processing in cardiac physiology.
Knöll R
Pflugers Arch. 2015 Jan;467(1):167-73