Jan Palmblad group

This research group started in 1975, moved to Huddinge in 1998, and still conducts translational research on the function of, and interactions between, neutrophils and endothelial cells, cells constituting an important part of the acute inflammatory response.

In addition, the group pursues research on effect of omega-3 fatty acids on inflammation in Alzheimer´s disease, on mechanisms for acute drug-induced and chronic neutropenias, on angiogenesis in hematological and gynecological disorders and on Gaucher´s disease.

Studies of effects of leukotrienes have been a red line since the start of the research group.

The research is translational, involving expertise in hematology, rheumatology, basic chemistry, nutrition etc.


Jan Palmblad, Group Leader
Inger Vedin, Leg. BMA, PhD
Daniel Tesfa, MD, PhD
Miriam Mints, MD, PhD, Associate member
Eva Zetterberg, MD, PhD, Associate member

Maria Åström, MD, PhD, Associate member

Maciej Machaczka, MD, PhD, Associate member
Tommy Cederholm, Professor, Associate member

Alumni members

Among alumni (and present) members are Ingiäld Hafström, Katarina Le Blanc, Ann-Mari Udén-Blohmé, Bo Ringertz, Hans Gyllenhammar, Richard Lerner, Johan Bratt, Jan Samuelsson, Eva Ottosson, Marianne Keisu, Gerd Lärfars, Lars Kanerud, Anders Åhlin, Mikael Heimburger, Anders Sondén, Karl-Gustav Kölbeck, Göran Carlsson, Gerd Lärfars, Anne-Sofie Johansson, Eva Zetterberg and Inger Vedin. More than 20 PhD dissertations originate from this research group.

Selected publications

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Pericyte coverage of abnormal blood vessels in myelofibrotic bone marrows.
Zetterberg E, Vannucchi A, Migliaccio A, Vainchenker W, Tulliez M, Dickie R, et al
Haematologica 2007 May;92(5):597-604

Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial.
Freund-Levi Y, Eriksdotter-Jönhagen M, Cederholm T, Basun H, Faxén-Irving G, Garlind A, et al
Arch. Neurol. 2006 Oct;63(10):1402-8

To give and take - life of a platelet.
Palmblad J
Blood 2009 Mar;113(12):2617

Involvement of a functional NADPH oxidase in neutrophils and macrophages during programmed cell clearance: implications for chronic granulomatous disease.
Sanmun D, Witasp E, Jitkaew S, Tyurina Y, Kagan V, Ahlin A, et al
Am. J. Physiol., Cell Physiol. 2009 Sep;297(3):C621-31

Subcellular localization of leukotriene receptors in human endothelial cells.
Johansson A, Haeggström J, Hultenby K, Palmblad J
Exp. Cell Res. 2010 Oct;316(17):2790-6

Expression of angiopoietins 1, 2 and their common receptor tie-2 in relation to the size of endothelial lining gaps and expression of VEGF and VEGF receptors in idiopathic menorrhagia.
Mints M, Blomgren B, Palmblad J
Fertil. Steril. 2010 Jul;94(2):701-7

HematologyRegenerative Medicine