Stress and cancer development and prognosis

The goal of this project was to examine whether traumatic life events are associated with the cancer risk and survival

Project description

Background: Results from observational studies suggest that traumatic life events may influence both the risk and prognosis of malignant disease. Evidence from animal studies indicates that immunological tumour defences are weakened following severe stress.

Material: The Swedish National Cancer Register, the Cause of Death Register, the Multi Generational register, the Population Register.

Project leader


Mats Lambe

Phone: +46-(0)8-524 861 64
Organizational unit: Department of Medical Epidemiology and Biostatistics (MEB), C8

Project period: 2010-2014
Support: The Swedish Medical Research Council


Risk of infection-related cancers after the loss of a child: a follow-up study in Sweden.
Fang F, Fall K, Sparén P, Adami H, Valdimarsdóttir H, Lambe M, et al
Cancer Res. 2011 Jan;71(1):116-22
Loss of a parent and the risk of cancer in early life: a nationwide cohort study.
Kennedy B, Valdimarsdóttir U, Sundström K, Sparén P, Lambe M, Fall K, et al
Cancer Causes Control 2014 Apr;25(4):499-506