Publications related to Protein Science Facility

The following publications have been done with support from Protein Science Facility

2016 publications

  1. Generation and analyses of human synthetic antibody libraries and their application for protein microarrays.
    Säll A, Walle M, Wingren C, Müller S, Nyman T, Vala A, et al
    Protein Eng. Des. Sel. 2016 Oct;29(10):427-37
  2. NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.
    Valerie N, Hagenkort A, Page B, Masuyer G, Rehling D, Carter M, et al
    Cancer Res. 2016 Sep;76(18):5501-11
  3. A ribonucleotide reductase inhibitor with deoxyribonucleoside-reversible cytotoxicity.
    Crona M, Codó P, Jonna V, Hofer A, Fernandes A, Tholander F
    Mol Oncol 2016 Nov;10(9):1375-1386
  4. Mutation-Induced Population Shift in the MexR Conformational Ensemble Disengages DNA Binding: A Novel Mechanism for MarR Family Derepression.
    Anandapadamanaban M, Pilstål R, Andresen C, Trewhella J, Moche M, Wallner B, et al
    Structure 2016 Aug;24(8):1311-21
  5. Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
    Brunner K, Maric S, Reshma R, Almqvist H, Seashore-Ludlow B, Gustavsson A, et al
    J. Med. Chem. 2016 Jul;59(14):6848-59
  6. The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity.
    Sandalova T, Lee M, Henriques-Normark B, Hesek D, Mobashery S, Mellroth P, et al
    Mol. Microbiol. 2016 Sep;101(6):954-67
  7. Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.
    Siitonen V, Selvaraj B, Niiranen L, Lindqvist Y, Schneider G, Metsä-Ketelä M
    Proc. Natl. Acad. Sci. U.S.A. 2016 May;113(19):5251-6
  8. Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis.
    Kouznetsova E, Kanno T, Karlberg T, Thorsell A, Wisniewska M, Kursula P, et al
    Structure 2016 May;24(5):789-96
  9. Novel mode of inhibition by D-tagatose 6-phosphate through a Heyns rearrangement in the active site of transaldolase B variants.
    Stellmacher L, Sandalova T, Schneider S, Schneider G, Sprenger G, Samland A
    Acta Crystallogr D Struct Biol 2016 Apr;72(Pt 4):467-76
  10. CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil.
    Almqvist H, Axelsson H, Jafari R, Dan C, Mateus A, Haraldsson M, et al
    Nat Commun 2016 Mar;7():11040
  11. A saposin-lipoprotein nanoparticle system for membrane proteins.
    Frauenfeld J, Löving R, Armache J, Sonnen A, Guettou F, Moberg P, et al
    Nat. Methods 2016 Apr;13(4):345-51
  12. Coxsackievirus counters the host innate immune response by blocking type III interferon expression.
    Lind K, Svedin E, Domsgen E, Kapell S, Laitinen O, Moll M, et al
    J. Gen. Virol. 2016 Jun;97(6):1-12
  13. Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family.
    Mills S, Silvander C, Cozier G, Trésaugues L, Nordlund P, Potter B
    Biochemistry 2016 Mar;55(9):1384-97
  14. Identification of Inhibitors of Pseudomonas aeruginosa Exotoxin-S ADP-Ribosyltransferase Activity.
    Pinto A, Ebrahimi M, Saleeb M, Forsberg , Elofsson M, Schüler H
    J Biomol Screen 2016 Jul;21(6):590-5
  15. Crystal structure of the flavoenzyme PA4991 from Pseudomonas aeruginosa.
    Jacewicz A, Schnell R, Lindqvist Y, Schneider G
    Acta Crystallogr F Struct Biol Commun 2016 Feb;72(Pt 2):105-11
  16. The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer.
    Hafstrand I, Doorduijn E, Duru A, Buratto J, Oliveira C, Sandalova T, et al
    J. Immunol. 2016 Mar;196(5):2327-34
  17. The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a--an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity.
    Lim S, Yeung K, Trésaugues L, Ling T, Nordlund P
    FEBS J. 2016 Mar;283(6):1107-23
  18. Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.
    Llona-Minguez S, Höglund A, Jacques S, Johansson L, Calderón-Montaño J, Claesson M, et al
    J. Med. Chem. 2016 Feb;59(3):1140-8
  19. A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase.
    Brock J, Hamberg M, Balagunaseelan N, Goodman M, Morgenstern R, Strandback E, et al
    Proc. Natl. Acad. Sci. U.S.A. 2016 Jan;113(4):972-7

2015 publications

  1. Structural insights into the DNA-binding specificity of E2F family transcription factors.
    Morgunova E, Yin Y, Jolma A, Dave K, Schmierer B, Popov A, et al
    Nat Commun 2015 Dec;6():10050
  2. Engineering a thermostable Halothermothrix orenii β-glucosidase for improved galacto-oligosaccharide synthesis.
    Hassan N, Geiger B, Gandini R, Patel B, Kittl R, Haltrich D, et al
    Appl. Microbiol. Biotechnol. 2016 Apr;100(8):3533-43
  3. DNA-dependent formation of transcription factor pairs alters their binding specificity.
    Jolma A, Yin Y, Nitta K, Dave K, Popov A, Taipale M, et al
    Nature 2015 Nov;527(7578):384-8
  4. Exploring water as building bricks in enzyme engineering.
    Hendil-Forssell P, Martinelle M, Syrén P
    Chem. Commun. (Camb.) 2015 Dec;51(97):17221-4
  5. Structure of the Glycosyltransferase Ktr4p from Saccharomyces cerevisiae.
    Possner D, Claesson M, Guy J
    PLoS ONE 2015 ;10(8):e0136239
  6. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2.
    Carter M, Jemth A, Hagenkort A, Page B, Gustafsson R, Griese J, et al
    Nat Commun 2015 Aug;6():7871
  7. Half-of-the-Sites Reactivity of the Castor Δ9-18:0-Acyl Carrier Protein Desaturase.
    Liu Q, Chai J, Moche M, Guy J, Lindqvist Y, Shanklin J
    Plant Physiol. 2015 Sep;169(1):432-41
  8. Structural basis for cellobiose dehydrogenase action during oxidative cellulose degradation.
    Tan T, Kracher D, Gandini R, Sygmund C, Kittl R, Haltrich D, et al
    Nat Commun 2015 Jul;6():7542
  9. Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.
    Trésaugues L, Lundbäck T, Welin M, Flodin S, Nyman T, Silvander C, et al
    PLoS ONE 2015 ;10(6):e0131507
  10. Trimeric microsomal glutathione transferase 2 displays one third of the sites reactivity.
    Ahmad S, Thulasingam M, Palombo I, Daley D, Johnson K, Morgenstern R, et al
    Biochim. Biophys. Acta 2015 Oct;1854(10 Pt A):1365-71
  11. Structure of the nuclease subunit of human mitochondrial RNase P.
    Reinhard L, Sridhara S, Hällberg B
    Nucleic Acids Res. 2015 Jun;43(11):5664-72
  12. Crystal structures of the kinase domain of the sulfate-activating complex in Mycobacterium tuberculosis.
    Poyraz , Brunner K, Lohkamp B, Axelsson H, Hammarström L, Schnell R, et al
    PLoS ONE 2015 ;10(3):e0121494
  13. High-resolution crystal structure of a polyextreme GH43 glycosidase from Halothermothrix orenii with α-L-arabinofuranosidase activity.
    Hassan N, Kori L, Gandini R, Patel B, Divne C, Tan T
    Acta Crystallogr F Struct Biol Commun 2015 Mar;71(Pt 3):338-45
  14. Structural characterization of substrate and inhibitor binding to farnesyl pyrophosphate synthase from Pseudomonas aeruginosa.
    Schmidberger J, Schnell R, Schneider G
    Acta Crystallogr. D Biol. Crystallogr. 2015 Mar;71(Pt 3):721-31
  15. Structural basis for lack of ADP-ribosyltransferase activity in poly(ADP-ribose) polymerase-13/zinc finger antiviral protein.
    Karlberg T, Klepsch M, Thorsell A, Andersson C, Linusson A, Schüler H
    J. Biol. Chem. 2015 Mar;290(12):7336-44
  16. Acid–Base Catalyst Discriminates between a Fructose 6-Phosphate Aldolase and a Transaldolase
    Stellmacher L, Sandalova T, Leptihn S, Schneider G, Sprenger GA, Samland AK
    ChemCatChem 2015, Oct 5; 7(19):3140-3151

2014 publications

  1.     An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein.
    Seijsing J, Lindborg M, Höidén-Guthenberg I, Bönisch H, Guneriusson E, Frejd F, et al
    Proc. Natl. Acad. Sci. U.S.A. 2014 Dec;111(48):17110-5
  2.     Effects of terminal dimethylation and metal coordination of proline-2-formylpyridine thiosemicarbazone hybrids on lipophilicity, antiproliferative activity, and hR2 RNR inhibition.
    Bacher F, Dömötör O, Kaltenbrunner M, Mojović M, Popović-Bijelić A, Gräslund A, et al
    Inorg Chem 2014 Dec;53(23):12595-609
  3.     A novel cytosolic NADH:quinone oxidoreductase from Methanothermobacter marburgensis.
    Ullmann E, Tan T, Gundinger T, Herwig C, Divne C, Spadiut O
    Biosci. Rep. 2014 Dec;34(6):e00167
  4.     Biochemical and structural characterization of a thermostable β-glucosidase from Halothermothrix orenii for galacto-oligosaccharide synthesis.
    Hassan N, Nguyen T, Intanon M, Kori L, Patel B, Haltrich D, et al
    Appl. Microbiol. Biotechnol. 2015 Feb;99(4):1731-44
  5.     Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2.
    Guettou F, Quistgaard E, Raba M, Moberg P, Löw C, Nordlund P
    Nat. Struct. Mol. Biol. 2014 Aug;21(8):728-31
  6.     Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family.
    Pinto A, Schüler H
    Curr. Top. Microbiol. Immunol. 2015 ;384():153-66
  7.     Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A.
    Dovega R, Tsutakawa S, Quistgaard E, Anandapadamanaban M, Löw C, Nordlund P
    PLoS ONE 2014 ;9(7):e101846
  8.     Structural basis for PTPA interaction with the invariant C-terminal tail of PP2A.
    Löw C, Quistgaard E, Kovermann M, Anandapadamanaban M, Balbach J, Nordlund P
    Biol. Chem. 2014 Jul;395(7-8):881-9
  9.     Structural basis for regulation of the human acetyl-CoA thioesterase 12 and interactions with the steroidogenic acute regulatory protein-related lipid transfer (START) domain.
    Swarbrick C, Roman N, Cowieson N, Patterson E, Nanson J, Siponen M, et al
    J. Biol. Chem. 2014 Aug;289(35):24263-74
  10.     Structural and functional characterization of ochratoxinase, a novel mycotoxin-degrading enzyme.
    Dobritzsch D, Wang H, Schneider G, Yu S
    Biochem. J. 2014 Sep;462(3):441-52
  11.     Crystal structure of human CRMP-4: correction of intensities for lattice-translocation disorder.
    Ponnusamy R, Lebedev A, Pahlow S, Lohkamp B
    Acta Crystallogr. D Biol. Crystallogr. 2014 Jun;70(Pt 6):1680-94
  12.     Functional and structural properties of a novel protein and virulence factor (Protein sHIP) in Streptococcus pyogenes.
    Wisniewska M, Happonen L, Kahn F, Varjosalo M, Malmström L, Rosenberger G, et al
    J. Biol. Chem. 2014 Jun;289(26):18175-88
  13.     Structure and inhibition of mouse leukotriene C4 synthase.
    Niegowski D, Kleinschmidt T, Ahmad S, Qureshi A, Mårback M, Rinaldo-Matthis A, et al
    PLoS ONE 2014 ;9(5):e96763
  14.     Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases.
    Trésaugues L, Silvander C, Flodin S, Welin M, Nyman T, Gräslund S, et al
    Structure 2014 May;22(5):744-55
  15.     MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
    Gad H, Koolmeister T, Jemth A, Eshtad S, Jacques S, Ström C, et al
    Nature 2014 Apr;508(7495):215-21
  16.     ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamics.
    Marteyn B, Karimova G, Fenton A, Gazi A, West N, Touqui L, et al
    MBio 2014 Mar;5(2):e00022-14
  17.     Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor.
    Stsiapanava A, Olsson U, Wan M, Kleinschmidt T, Rutishauser D, Zubarev R, et al
    Proc. Natl. Acad. Sci. U.S.A. 2014 Mar;111(11):4227-32
  18.     Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms.
    Raposo B, Dobritzsch D, Ge C, Ekman D, Xu B, Lindh I, et al
    J. Exp. Med. 2014 Mar;211(3):405-11
  19.     Design, synthesis, crystallographic studies, and preliminary biological appraisal of new substituted triazolo[4,3-b]pyridazin-8-amine derivatives as tankyrase inhibitors.
    Liscio P, Carotti A, Asciutti S, Karlberg T, Bellocchi D, Llacuna L, et al
    J. Med. Chem. 2014 Mar;57(6):2807-12
  20.     Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae.
    Mellroth P, Sandalova T, Kikhney A, Vilaplana F, Hesek D, Lee M, et al
    MBio 2014 Feb;5(1):e01120-13
  21.     Structural basis for binding of fluorinated glucose and galactose to Trametes multicolor pyranose 2-oxidase variants with improved galactose conversion.
    Tan T, Spadiut O, Gandini R, Haltrich D, Divne C
    PLoS ONE 2014 ;9(1):e86736
  22.     The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold.
    Schulte T, Löfling J, Mikaelsson C, Kikhney A, Hentrich K, Diamante A, et al
    Open Biol 2014 Jan;4():130090
  23.     Crystal structures of leukotriene C4 synthase in complex with product analogs: implications for the enzyme mechanism.
    Niegowski D, Kleinschmidt T, Olsson U, Ahmad S, Rinaldo-Matthis A, Haeggström J
    J. Biol. Chem. 2014 Feb;289(8):5199-207
  24.     Product formation controlled by substrate dynamics in leukotriene A4 hydrolase.
    Stsiapanava A, Tholander F, Kumar R, Qureshi A, Niegowski D, Hasan M, et al
    Biochim. Biophys. Acta 2014 Feb;1844(2):439-46
  25.     RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function.
    Böth D, Steiner E, Izumi A, Schneider G, Schnell R
    Biochem. J. 2014 Jan;457(1):33-41


2013 publications

  1.     Nanobody mediated crystallization of an archeal mechanosensitive channel.
    Löw C, Yau Y, Pardon E, Jegerschöld C, Wåhlin L, Quistgaard E, et al
    PLoS ONE 2013 ;8(10):e77984
  2.     Chemical probes to study ADP-ribosylation: synthesis and biochemical evaluation of inhibitors of the human ADP-ribosyltransferase ARTD3/PARP3.
    Lindgren A, Karlberg T, Ekblad T, Spjut S, Thorsell A, Andersson C, et al
    J. Med. Chem. 2013 Dec;56(23):9556-68
  3.     Metal-mediated crystallization of the xylose transporter XylE from Escherichia coli in three different crystal forms.
    Quistgaard E, Löw C, Moberg P, Nordlund P
    J. Struct. Biol. 2013 Nov;184(2):375-8
  4.     Discovery of an allosteric inhibitor binding site in 3-Oxo-acyl-ACP reductase from Pseudomonas aeruginosa.
    Cukier C, Hope A, Elamin A, Moynie L, Schnell R, Schach S, et al
    ACS Chem. Biol. 2013 Nov;8(11):2518-27
  5.     Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31.
    Quistgaard E, Löw C, Moberg P, Guettou F, Maddi K, Nordlund P
    PLoS ONE 2013 ;8(8):e71111
  6.     Structure-guided design of novel thiazolidine inhibitors of O-acetyl serine sulfhydrylase from Mycobacterium tuberculosis.
    Poyraz O, Jeankumar V, Saxena S, Schnell R, Haraldsson M, Yogeeswari P, et al
    J. Med. Chem. 2013 Aug;56(16):6457-66
  7.     Structural insights into substrate recognition in proton-dependent oligopeptide transporters.
    Guettou F, Quistgaard E, Trésaugues L, Moberg P, Jegerschöld C, Zhu L, et al
    EMBO Rep. 2013 Sep;14(9):804-10
  8.     High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation.
    Anandapadamanaban M, Andresen C, Helander S, Ohyama Y, Siponen M, Lundström P, et al
    Nat. Struct. Mol. Biol. 2013 Aug;20(8):1008-14
  9.     Substrate specificity and oligomerization of human GMP synthetase.
    Welin M, Lehtiö L, Johansson A, Flodin S, Nyman T, Trésaugues L, et al
    J. Mol. Biol. 2013 Nov;425(22):4323-33
  10.     Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates.
    Chen M, Lohkamp B, Schnell R, Lescar J, Schneider G
    PLoS ONE 2013 ;8(6):e66936
  11.     PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.
    Lindgren A, Karlberg T, Thorsell A, Hesse M, Spjut S, Ekblad T, et al
    ACS Chem. Biol. 2013 Aug;8(8):1698-703
  12.     Enzymatic production of 'monoclonal stoichiometric' single-stranded DNA oligonucleotides.
    Ducani C, Kaul C, Moche M, Shih W, Högberg B
    Nat. Methods 2013 Jul;10(7):647-52
  13.     Structural insights into the UbiD protein family from the crystal structure of PA0254 from Pseudomonas aeruginosa.
    Jacewicz A, Izumi A, Brunner K, Schnell R, Schneider G
    PLoS ONE 2013 ;8(5):e63161
  14.     Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
    Quistgaard E, Löw C, Moberg P, Trésaugues L, Nordlund P
    Nat. Struct. Mol. Biol. 2013 Jun;20(6):766-8
  15.     Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase.
    Lim S, Chen D, Teo H, Roos A, Jansson A, Nyman T, et al
    J. Lipid Res. 2013 Jun;54(6):1630-43
  16.     The crystal structure of the lumenal domain of Erv41p, a protein involved in transport between the endoplasmic reticulum and Golgi apparatus.
    Biterova E, Svärd M, Possner D, Guy J
    J. Mol. Biol. 2013 Jun;425(12):2208-18
  17.     Structure of LdtMt2, an L,D-transpeptidase from Mycobacterium tuberculosis.
    Böth D, Steiner E, Stadler D, Lindqvist Y, Schnell R, Schneider G
    Acta Crystallogr. D Biol. Crystallogr. 2013 Mar;69(Pt 3):432-41
  18.     Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains.
    Forst A, Karlberg T, Herzog N, Thorsell A, Gross A, Feijs K, et al
    Structure 2013 Mar;21(3):462-75
  19.     Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway.
    Oja T, Niiranen L, Sandalova T, Klika K, Niemi J, Mäntsälä P, et al
    Proc. Natl. Acad. Sci. U.S.A. 2013 Jan;110(4):1291-6
  20.     The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
    Moynie L, Schnell R, McMahon S, Sandalova T, Boulkerou W, Schmidberger J, et al
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2013 Jan;69(Pt 1):25-34


2012 publications

  1.     Crystal structure of NirD, the small subunit of the nitrite reductase NirbD from Mycobacterium tuberculosis at 2.0 Å resolution.
    Izumi A, Schnell R, Schneider G
    Proteins 2012 Dec;80(12):2799-803
  2.     Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics.
    Allerbring E, Duru A, Uchtenhagen H, Madhurantakam C, Tomek M, Grimm S, et al
    Eur. J. Immunol. 2012 Nov;42(11):2990-3000
  3.     Discovery of ligands for ADP-ribosyltransferases via docking-based virtual screening.
    Andersson C, Karlberg T, Ekblad T, Lindgren A, Thorsell A, Spjut S, et al
    J. Med. Chem. 2012 Sep;55(17):7706-18
  4.     High-resolution insights into binding of unfolded polypeptides by the PPIase chaperone SlpA.
    Quistgaard E, Nordlund P, Löw C
    FASEB J. 2012 Oct;26(10):4003-13
  5.     Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1.
    Löw C, Jegerschöld C, Kovermann M, Moberg P, Nordlund P
    PLoS ONE 2012 ;7(6):e38244
  6.     Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.
    Egeblad L, Welin M, Flodin S, Gräslund S, Wang L, Balzarini J, et al
    PLoS ONE 2012 ;7(5):e37724
  7.     Inflammation-associated nitrotyrosination affects TCR recognition through reduced stability and alteration of the molecular surface of the MHC complex.
    Madhurantakam C, Duru A, Sandalova T, Webb J, Achour A
    PLoS ONE 2012 ;7(3):e32805
  8.     Tetrahydrodipicolinate N-succinyltransferase and dihydrodipicolinate synthase from Pseudomonas aeruginosa: structure analysis and gene deletion.
    Schnell R, Oehlmann W, Sandalova T, Braun Y, Huck C, Maringer M, et al
    PLoS ONE 2012 ;7(2):e31133
  9.     Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.
    Wahlberg E, Karlberg T, Kouznetsova E, Markova N, Macchiarulo A, Thorsell A, et al
    Nat. Biotechnol. 2012 Feb;30(3):283-8
  10.     High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C.
    Willander H, Askarieh G, Landreh M, Westermark P, Nordling K, Keränen H, et al
    Proc. Natl. Acad. Sci. U.S.A. 2012 Feb;109(7):2325-9

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