Laboratories for Chemical Biology Karolinska Institutet (LCBKI

LCBKI is a KI core facility, established in 2010 and along with Laboratories for Chemical Biology Umeå (LCBU), a part of a national consortium for chemical biology research - Chemical Biology Consortium Sweden (CBCS) and a national infrastructure at SciLifeLab. The facility comprises compound handling labs (hosting the SciLifeLab compound collection of about 200 000 molecules), screening labs (microtiter format liquid handling robotics and a wide range of plate readers), and chemistry labs (equipment and instrumentation for organic chemistry synthesis and analysis). The majority of the scientists at CBCS have extensive background from the pharmaceutical industry and solid experience in the development of bioactive molecules.

Services

Main services that LCBKI/CBCS offers are:

  1. assay development and formatting of biochemical and cellular assays for screening purposes
  2. high-throughput screening of small-molecule libraries
  3. hit validation and chemical optimisation towards high-quality chemical tools
  4. target identification and enabling chemistry.

Contact

Senior researcher

Anna-Lena Gustavsson

Phone: +46-(0)8-524 812 87
Organizational unit: LCBKI
E-mail: Anna-Lena.Gustavsson@ki.se

Visit our webpage www.cbcs.se.

Staff

Helena AlmqvistResearch engineer
Hanna AxelssonResearch engineer
Anna-Lena GustavssonSenior researcher
Lars HammarströmSenior researcher
Martin HaraldssonSenior researcher
Annika Jenmalm JensenSenior researcher
Therese JernevadAdministrator
Lars JohanssonSenior researcher
Thomas LundbäckAssociated
Magdalena OtrockaProject Manager
Brinton Seashore-LudlowProject manager
Jawed ShafqatSenior researcher
Birger SjöbergSenior lab manager
Åsa SlevinResearch engineer
Michaela VallinProject Manager