Research group - Andrej Weintraub & Carl-Erik Nord
The research is focused on the influence of antibiotics on the human normal microflora.
The impact of the drugs is studied both on the short term bases (during and directly after the treatment) as well as on long-term bases. We are studying the development of resistance as well as the mechanisms of development of resistance. We are also studying the infections caused by Clostridim difficile infection (CDI). The main aim is to find out why some patients suffer from multiple recurrences of the disease. Clinical trials with antibiotics on healthy volunteers may give an indication if a particular drug may increase the risk of CDI. Studies of the risk factors for multiple recurrences of CDI are important since thy cause a lot of sufferning for the patients as well as high costs for the health care system. Another part of our research concerns epidemiological studies on the cause of diarrhoea in children less than 5 years of age in developing countries. We also study the cell wall antigens in Gram-negative bacteria causing diarrhoeal diseases.
Research group leader Andrej Weintraub
Research group leader Carl-Erik Nord
|Andrej Weintraub||Professor/senior clinical chemist|
|Carl Erik Nord||Professor, senior|
|Lena Klingspor||Senior researcher|
- Culture of bacteria from the normal microflora on selective and non-selective media
- Isolation of resistant bacteria
- Determination of antibiotic sensitivity
- Determination of antibiotic concentration in different body fluids
- Characterisation of bacterial isolates (aerobic and anaerobic) by:
- Gas-liquid chromatography
EU, Swedish Research Council, Swedish Society of Medicine, Pharmaceutical companies
Medical and odontology students, Nurses, Technicians
Antibiotic resistance patterns of intestinal Escherichia coli isolates from Nicaraguan children.
J. Med. Microbiol. 2011 Feb;60(Pt 2):216-22
Effect of telavancin on human intestinal microflora.
Int. J. Antimicrob. Agents 2011 Dec;38(6):474-9
Effect of ceftaroline on normal human intestinal microflora.
Antimicrob. Agents Chemother. 2010 May;54(5):1811-4
Molecular and clinical characteristics of Clostridium difficile infection in a University Hospital in Shanghai, China.
Clin. Infect. Dis. 2008 Dec;47(12):1606-8