Research group - Andrej Weintraub & Carl-Erik Nord

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The research is focused on the influence of antibiotics on the human normal microflora.

The impact of the drugs is studied both on the short term bases (during and directly after the treatment) as well as on long-term bases. We are studying the development of resistance as well as the mechanisms of development of resistance. We are also studying the infections caused by Clostridim difficile infection (CDI). The main aim is to find out why some patients suffer from multiple recurrences of the disease. Clinical trials with antibiotics on healthy volunteers may give an indication if a particular drug may increase the risk of CDI. Studies of the risk factors for multiple recurrences of CDI are important since thy cause a lot of sufferning for the patients as well as high costs for the health care system. Another part of our research concerns epidemiological studies on the cause of diarrhoea in children less than 5 years of age in developing countries. We also study the cell wall antigens in Gram-negative bacteria causing diarrhoeal diseases.

Research group leader Andrej Weintraub

Professor/senior clinical chemist

Andrej Weintraub

Phone: 08-524 837 38
Organizational unit: Division of Clinical Microbiology

Research group leader  Carl-Erik Nord

Professor, senior

Carl Erik Nord

Phone: 08-524 836 69
Organizational unit: Division of Clinical Microbiology

Group members

Andrej WeintraubProfessor/senior clinical chemist
Carl Erik NordProfessor, senior
Cristina OpricaAssociated
Lena KlingsporSenior researcher
Monica SörenssonAssociated

Research techniques

  • Culture of bacteria from the normal microflora on selective and non-selective media
  • Isolation of resistant bacteria
  • Determination of antibiotic sensitivity
  • Determination of antibiotic concentration in different body fluids
  • Characterisation of bacterial isolates (aerobic and anaerobic) by:
    • PCR
    • RT-PCR
    • Gas-liquid chromatography

External funding

EU, Swedish Research Council, Swedish Society of Medicine, Pharmaceutical companies

Teaching assignments

Medical and odontology students, Nurses, Technicians

Selected publications

Antibiotic resistance patterns of intestinal Escherichia coli isolates from Nicaraguan children.
Amaya E, Reyes D, Vilchez S, Paniagua M, Möllby R, Nord C, et al
J. Med. Microbiol. 2011 Feb;60(Pt 2):216-22

Structure of the O-polysaccharide of Vibriocholerae O43 containing a new monosaccharide derivative, 4-(N-acetyl-l-allothreonyl)amino-4,6-dideoxy-D-glucose.
Perepelov A, Kocharova N, Knirel Y, Jansson P, Weintraub A
Carbohydr. Res. 2011 Feb;346(3):430-3

Effect of telavancin on human intestinal microflora.
Rashid M, Weintraub A, Nord C
Int. J. Antimicrob. Agents 2011 Dec;38(6):474-9

Effect of ceftaroline on normal human intestinal microflora.
Panagiotidis G, Bäckström T, Asker-Hagelberg C, Jandourek A, Weintraub A, Nord C
Antimicrob. Agents Chemother. 2010 May;54(5):1811-4

Molecular and clinical characteristics of Clostridium difficile infection in a University Hospital in Shanghai, China.
Huang H, Wu S, Wang M, Zhang Y, Fang H, Palmgren A, et al
Clin. Infect. Dis. 2008 Dec;47(12):1606-8

Infectious Disease MedicineMicrobiology