• Epidemiolgy
  • Brain MRI

The Neuroepidemiology Research Group

About us

We are a multidisciplinary research group interested in different aspects of epidemiology of Multiple Sclerosis (MS). Our group consisted of epidemiologists, geneticists, neurologists, immunologists and mathematicians. The group addresses questions facing patients, physicians and researchers with an aim to forge understanding of mechanisms behind development of MS and its clinical course. We aim to foster cross-disciplinary collaborations between researchers, patients and clinicians through several national and international projects.

Our research

Multiple Sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system affecting around one million people world-wide. The disease progression varies between patients but often causes different degrees of disability. In the MS group at CMM we aim to contribute to the urgently needed advancement of MS research by applying translational methods based on large patient cohorts. In this way hope to cast new light on the etiology of MS by seeking to understand the genetic components of the disease. We are also investigating a possible viral etiology of the disease using experimental systems. MS treatments have improved significantly over the last decade, but they are still only partially effective and/or hampered by side effects, leaving a great clinical need for intensified research on disease mechanisms and novel therapeutics. 

Genetics of MS

 

What triggers MS?

 

What provokes progression?

 

What are the social and economic consequences of MS?

 

 

Listen to an inspirational lecture by our group leader

Listen to an inspirational lecture by our group leader, professor Jan Hillert. He is telling us about a new promising clinical research field. 

Digging for gold in registries and biobanks

 

Group Members

Group Leader 

Head of department

Jan Hillert

Organizational unit: Department of Clinical Neuroscience (CNS), K8
E-mail: Jan.Hillert@ki.se

Project Manager

Project manager

Anna Glaser

Phone: +46-(0)76-555 72 53
Organizational unit: Neuro Hillert
E-mail: anna.glaser@ki.se

Associates

Assistant professor

Ryan Ramanujam

Organizational unit: Department of Clinical Neuroscience (CNS), K8
E-mail: Ryan.Ramanujam@ki.se

Katharina Fink

Katharina's research is driven by the contact with her patients, addressing relevant clinical knowledge gaps. Advocating female patients with MS she is interested in research directed at pregnancy, health and socioeconomic outcomes in mothers with MS, as well as their children. In line with this, she is currently involved in a study investigating the risk profile of rituximab in women with MS that have been exposed to rituximab around their pregnancy. The study looks at delivery complications, birth defects and adverse birth outcomes in patients´ children, as well as structured long-term outcomes. 

Associated

Katarina Fink

Organizational unit: Neuro Hillert
E-mail: katarina.fink@ki.se

Kerstin Imrell

Associated

Kerstin Imrell

Organizational unit: Neuro Hillert
E-mail: Kerstin.Imrell@ki.se

Sahl Khalid Bedri

Graduate Student

Sahl Khalid Bedri

E-mail: sahl.bedri@ki.se

Andrius Kavaliunas

Postdoc

Andrius Kavaliunas

Organizational unit: Neuro Hillert
E-mail: andrius.kavaliunas@ki.se

Tim Spelman

Assistant professor

Tim Spelman

Organizational unit: Neuro Hillert
E-mail: tim.spelman@ki.se

Leszek Stawiarz

Project coordinator

Leszek Stawiarz

Phone: +46-(0)76-852 23 29
Organizational unit: Neuro Hillert
E-mail: Leszek.Stawiarz@ki.se

Virginija Danylaité Karrenbauer

Associated

Virginija Danylaité Karrenbauer

Organizational unit: Neuro Hillert
E-mail: Virginija.Karrenbauer@ki.se

Ali Manouchehrinia

Postdoc

Ali Manouchehrinia

Organizational unit: Neuro Hillert
E-mail: ali.manouchehrinia@ki.se

 

Latest Publications

Age Related Multiple Sclerosis Severity Score: Disability ranked by age.
Manouchehrinia A, Westerlind H, Kingwell E, Zhu F, Carruthers R, Ramanujam R, et al
Mult. Scler. 2017 Jan;():1352458517690618

Similar familial risk in multiple sclerosis subgroups.
Song J, Karrenbauer V, Manouchehrinia A, Almqvist C, Hillert J, Westerlind H
Mult. Scler. 2017 Jan;():1352458516684214

Income in Multiple Sclerosis Patients with Different Disease Phenotypes.
Kavaliunas A, Manouchehrinia A, Danylaite Karrenbauer V, Gyllensten H, Glaser A, Alexanderson K, et al
PLoS ONE 2017 ;12(1):e0169460

Clinical course of multiple sclerosis: A nationwide cohort study.
Manouchehrinia A, Beiki O, Hillert J
Mult. Scler. 2016 Dec;():1352458516681197

Importance of early treatment initiation in the clinical course of multiple sclerosis.
Kavaliunas A, Manouchehrinia A, Stawiarz L, Ramanujam R, Agholme J, Hedström A, et al
Mult. Scler. 2017 Aug;23(9):1233-1240

The Swedish MS registry – clinical support tool and scientific resource.
Hillert J, Stawiarz L
Acta Neurol. Scand. 2015 ;132(199):11-9

A significant decrease in diagnosis of primary progressive multiple sclerosis: A cohort study.
Westerlind H, Stawiarz L, Fink K, Hillert J, Manouchehrinia A
Mult. Scler. 2016 Jul;22(8):1071-9

The influence of immunomodulatory treatment on the clinical course of multiple sclerosis.
Kavaliunas A, Stawiarz L, Hedbom J, Glaser A, Hillert J
Adv. Exp. Med. Biol. 2015 ;822():19-24

New data identify an increasing sex ratio of multiple sclerosis in Sweden.
Westerlind H, Boström I, Stawiarz L, Landtblom A, Almqvist C, Hillert J
Mult. Scler. 2014 Oct;20(12):1578-83

Age-specific sex ratio of multiple sclerosis in the National Swedish MS Register (SMSreg).
Boström I, Stawiarz L, Landtblom A
Mult. Scler. 2014 Apr;20(4):513-4

 

Find us

Visiting address: Widerströmska Huset, Tomtebodavägen 18a, 5 Tr, 171 77 Stockholm, Sweden

 

 

Clinical NeuroscienceEpidemiologyGeneticsHuman subject researchNeurodegenerative diseasesNeuroimmunologyNeurologyStatistics