Per Montan´s research group

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Diseases of the Anterior Eye Parts

This group consists of three main researchers, all active physicians at St Eriks Hospital.

Per Montan´s group is studying complications after cataract surgery such as inflammation, infection and corneal effects. In addition, research is carried out on chronic eye allergy. The group includes five doctors at St Erik´s eye hospital and colleagues in the Swedish Cataract Registry as well as at Mölndal and Umeå eye clinics. Other partners are Clinical Microbiology and Clinical Immunology at the Karolinska University Hospital.

Stefan Löfgren is studying a disease mechanism, the production of so-called free radicals, which are considered to be important for several common eye diseases, such as cataract. Using animal models he is studying the formation of free radicals but also how the tissue tries to repair their harmful effects. The goal is to find methods which could ultimately reduce cataract development in humans and perhaps cure cataract medically. The group collaborates with Uppsala University Hospital, The Lincoln-Nebraska University, USA and The University Hospital of Bonn in Germany.

Gysbert van Setten´s group is studying the growth- and healing factors in tears, in the aqueous humor and in the vitreous. The group is examining different effects on a cellular level of cataract and glaucoma surgery. Furthermore, the group is conducting research on the healing of corneal wounds, the effect of the usage of contact lenses on the cornea and the pathogenic factors of try eyes. Associate professor van Setten has patents and he has also submitted patent applications regarding innovations within the eye area. The group consisting of three doctors from St Erik´s eye hospital has cooperation with Karolinska Institutet and with USA, Greece and Austria abroad.

Research Projects

  • Complications after cataract surgery such as inflammation, infection and corneal effects
  • Cronic eye allergy

Selected Publications

Tacrolimus ointment vs steroid ointment for eyelid dermatitis in patients with atopic keratoconjunctivitis.
Nivenius E, van der Ploeg I, Jung K, Chryssanthou E, van Hage M, Montan P
Eye (Lond) 2007 Jul;21(7):968-75

Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice.
Samolov B, Steen B, Seregard S, van der Ploeg I, Montan P, Kvanta A
Exp. Eye Res. 2005 Feb;80(2):159-66

No apparent association between periocular and ocular microcolonization and the degree of inflammation in patients with atopic keratoconjunctivitis.
Nivenius E, Montan P, Chryssanthou E, Jung K, van Hage-Hamsten M, van der Ploeg I
Clin. Exp. Allergy 2004 May;34(5):725-30

Respiratory syncytial virus and chlamydia are not detectable by PCR in ongoing vernal keratoconjunctivitis.
Koulikovska M, van der Ploeg I, Herrmann B, Montan P
Ocul. Immunol. Inflamm. 2001 Dec;9(4):253-7

Group members

Branka SamolovAssociated
Elin BohmanGraduate Student
Emma FrilingGraduate Student
Eva Dafgård KoppAssociated
Gysbert van SettenAssociated
Marcelo AyalaAssociated
Oran AbdiuGraduate Student
Per MontanAssociated, Research team leader
Stefan LöfgrenAssociated